Browse our latest research

Page 936 of 1,810
    1. Neuroscience

    Temporal evolution of single-cell transcriptomes of Drosophila olfactory projection neurons

    Qijing Xie, Maria Brbic ... Hongjie Li
    Single-cell transcriptomes of Drosophila olfactory projection neurons correspond to previously defined cell types, exhibit unique characteristics at different developmental stages, and reveal cell-type-specific gene expression programs in development and function.
    1. Immunology and Inflammation

    Peripheral natural killer cells in chronic hepatitis B patients display multiple molecular features of T cell exhaustion

    Marie Marotel, Marine Villard ... Antoine Marçais
    Similar to T cell exhaustion, natural killer cell dysfunction in chronic hepatitis B patients results from deregulated calcium pathway.
    1. Evolutionary Biology

    The rise and fall of the ancient northern pike master sex-determining gene

    Qiaowei Pan, Romain Feron ... Yann Guiguen
    Tracing the evolution of an old master sex determination gene reveals a diversity of sex determination transitions, including a complete Y chromosome loss, among an old teleost order (Esociformes).
    1. Cell Biology

    TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin

    Fernando R Balestra, Andrés Domínguez-Calvo ... Pierre Gönczy
    TRIM37 prevents the formation of centriolar protein assemblies through an atypical de novo assembly pathway that would otherwise threaten genome integrity.
    1. Developmental Biology
    2. Neuroscience

    Comparison of induced neurons reveals slower structural and functional maturation in humans than in apes

    Maria Schörnig, Xiangchun Ju ... Elena Taverna
    Neurons mature slower in humans than in other non-human primates.
    1. Physics of Living Systems
    2. Immunology and Inflammation

    Early life imprints the hierarchy of T cell clone sizes

    Mario U Gaimann, Maximilian Nguyen ... Andreas Mayer
    The rapid development of immune memory in infancy shapes the composition of T cell defenses throughout the human lifespan.
    1. Plant Biology

    A fungal member of the Arabidopsis thaliana phyllosphere antagonizes Albugo laibachii via a GH25 lysozyme

    Katharina Eitzen, Priyamedha Sengupta ... Gunther Doehlemann
    A basidiomycete yeast closely related to fungal smuts is an antagonistic microbe in the Arabidopsis leaf phyllosphere that inhibits infection by Albugo laibachii via a GH25 hydrolase with lysozyme activity.
    1. Epidemiology and Global Health

    Model-based spatial-temporal mapping of opisthorchiasis in endemic countries of Southeast Asia

    Ting-Ting Zhao, Yi-Jing Feng ... Ying-Si Lai
    High-resolution risk estimates of opisthorchiasis were produced in major endemic countries of Southeast Asia, providing valuable information for guiding disease control and serving as a baseline for future progress assessment.
    1. Neuroscience

    Activation of MAP3K DLK and LZK in Purkinje cells causes rapid and slow degeneration depending on signaling strength

    Yunbo Li, Erin M Ritchie ... Yishi Jin
    The activity levels of two closely related MAPKKK are differentially regulated in Purkinje neuron survival.
    1. Neuroscience

    The distinct roles of calcium in rapid control of neuronal glycolysis and the tricarboxylic acid cycle

    Carlos Manlio Díaz-García, Dylan J Meyer ... Gary Yellen
    When neurons are stimulated, calcium entry into mitochondria upregulates mitochondrial energy production, but glycolytic energy production in the cytosol is stimulated by elevated energy demand, not Ca2+ signaling.