Browse our latest research

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    1. Ecology

    Diversity-decomposition relationships in forests worldwide

    Liang Kou, Lei Jiang ... Huimin Wang
    Carbon dynamics and the relative availability of key nutrients during litter decomposition are modified by changing biodiversity in the Earth’s forests.
    1. Evolutionary Biology
    2. Neuroscience

    Divergent sensory investment mirrors potential speciation via niche partitioning across Drosophila

    Ian W Keesey, Veit Grabe ... Bill S Hansson
    Phototaxis and courtship behavioral preferences reflect strong correlation with differences in olfactory and visual nervous system investment across five monophyletic Drosophila species, and could help explain their speciation events.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens

    George Ueda, Aleksandar Antanasijevic ... David Baker
    De novo protein nanoparticles were designed from scratch to present viral glycoprotein antigens, providing a systematic way to study the influence of antigen presentation geometry on immune response.
    1. Developmental Biology

    A novel function of R-spondin1 in regulating estrogen receptor expression independent of Wnt/β-catenin signaling

    Ajun Geng, Ting Wu ... Yi Arial Zeng
    Wnt/β-Catenin independent role of Rspo1 in physiological condition is revealed.
    1. Microbiology and Infectious Disease

    Expression of different L1 isoforms of Mastomys natalensis papillomavirus as mechanism to circumvent adaptive immunity

    Yingying Fu, Rui Cao ... Daniel Hasche
    Cutaneous papillomaviruses potentially escape humoral immune response by synthesizing an alternative major capsid protein isoform during the initial course of infection that is unable to induce neutralizing antibodies.
    1. Neuroscience
    2. Medicine

    Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women

    Stavros Trakoshis, Pablo Martínez-Cañada ... Michael V Lombardo
    Excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic males versus females.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Real-time in vivo imaging of extracellular ATP in the brain with a hybrid-type fluorescent sensor

    Nami Kitajima, Kenji Takikawa ... Kenzo Hirose
    Hybrid-type fluorescent ATP sensor showing submicromolar affinity, a large fluorescence response, high selectivity and pH-independence visualized extracellular ATP dynamics in the brain of living mice with high spatiotemporal resolution.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    S-phase-independent silencing establishment in Saccharomyces cerevisiae

    Davis Goodnight, Jasper Rine
    Cell-cycle progression is crucial for heterochromatin formation in budding yeast because S phase promotes the removal of active chromatin marks.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Drosophila seminal sex peptide associates with rival as well as own sperm, providing SP function in polyandrous females

    Snigdha Misra, Mariana F Wolfner
    A seminal protein from a mating-male can bind sperm previously stored in his mate, providing direct benefits to the sperm from the prior male that mated with her.
    1. Neuroscience

    Obesity causes selective and long-lasting desensitization of AgRP neurons to dietary fat

    Lisa R Beutler, Timothy V Corpuz ... Zachary A Knight
    Neurons that promote hunger become desensitized to dietary fat in obesity.