Browse our latest research

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    1. Computational and Systems Biology
    2. Neuroscience

    A sensorimotor model shows why a spectral jamming avoidance response does not help bats deal with jamming

    Omer Mazar, Yossi Yovel
    An elaborated bat-predator model shows that even in high bat-densities, bats can successfully catch flying insects and that changing their signals’ frequency is not necessary for dealing with sensory interference.
    1. Neuroscience

    α-synuclein strains that cause distinct pathologies differentially inhibit proteasome

    Genjiro Suzuki, Sei Imura ... Masato Hasegawa
    One α-synuclein strain inhibited proteasome activity and induced apparent pathologies, while the other did not, indicating a strain-dependent toxicity of α-synuclein aggregates, which support a prion-like behavior of α-synuclein.
    1. Cancer Biology

    Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma

    Allison N Lau, Zhaoqi Li ... Matthew G Vander Heiden
    Isotope tracing into macromolecules enables functional analysis of metabolism in specific cell populations in tumors and provides insight into metabolic differences between cancer and stromal cells in their endogenous microenvironment.
    1. Neuroscience

    Improving a probabilistic cytoarchitectonic atlas of auditory cortex using a novel method for inter-individual alignment

    Omer Faruk Gulban, Rainer Goebel ... Federico de Martino
    Inter-individual human brain alignment that uses macro-anatomical priors in addition to cortical curvature improves micro-anatomical correspondence between auditory areas.
    1. Genetics and Genomics

    Cdc13 is predominant over Stn1 and Ten1 in preventing chromosome end fusions

    Zhi-Jing Wu, Jia-Cheng Liu ... Jin-Qiu Zhou
    Cdc13 prevents chromosomes from end-to-end fusion.
    1. Physics of Living Systems

    A minimal self-organisation model of the Golgi apparatus

    Quentin Vagne, Jean-Patrick Vrel, Pierre Sens
    An unbiased model for the self-organisation of the Golgi apparatus displays either anterograde vesicular transport or cisternal maturation depending on ratios of budding, fusion and biochemical conversion rates.
    1. Neuroscience

    Keratinocytes contribute to normal cold and heat sensation

    Katelyn E Sadler, Francie Moehring, Cheryl L Stucky
    Purinergic keratinocyte-to-sensory neuron signaling is a ubiquitous amplification mechanism that is required for normal mechanical, cold, and heat sensation in vivo.
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Transposase-assisted tagmentation of RNA/DNA hybrid duplexes

    Bo Lu, Liting Dong ... Chengqi Yi
    Tn5 transposase has direct tagmentation activity towards RNA/DNA hybrids, which is harnessed as a more convenient and faster RNA-seq library construction method and will benefit RNA and chromatin research.
    1. Neuroscience

    Microglial calcium signaling is attuned to neuronal activity in awake mice

    Anthony D Umpierre, Lauren L Bystrom ... Long-Jun Wu
    Microglial processes engage calcium signaling in response to hyper- or hypo-active shifts in neuronal activity.
    1. Ecology

    Biodiversity mediates the effects of stressors but not nutrients on litter decomposition

    Léa Beaumelle, Frederik De Laender, Nico Eisenhauer
    The consequences of real-world biodiversity change for ecosystem functioning depend on the type of global change driver and can be particularly significant when human activities decrease biodiversity.