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    1. Cancer Biology

    Gene Interactions: Developing a taxonomy for colorectal cancer

    Jiansong Fang, Dawei Wang, Xiude Fan
    Analyzing how gene interaction networks are perturbed in individuals can help identify different types of colorectal cancers, paving the way towards personalized care.
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    1. Microbiology and Infectious Disease

    Antimicrobial Resistance: Adapt or perish

    Rohan BH Williams
    Microbial communities in wastewater treatment plants provide insights into the development and mechanisms of antimicrobial resistance.
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    1. Neuroscience

    Hippocampus: Connecting to the long axis

    Bryan A Strange
    New study reveals how various regions of the human cortex connect to the hippocampus along its longer anterior-posterior axis, shedding light on the way this structure is functionally organized.
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    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Protein Expression: Finding abundance regulators

    Olivia Ozguc, Sibylle Vonesch
    A new pooled screening method in yeast allows scientists to probe how protein levels are regulated by mutating thousands of genes at once.
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    1. Physics of Living Systems

    Bacteria: Bringing cells to the edge

    Teng Wang, Lingchong You
    A network of open channels allows cells and molecular cargo to travel from the center to the periphery of lab-grown colonies of Pseudomonas aeruginosa, helping to eradicate competing species.
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    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Evolution: A life LINE for large viruses

    Eugene V Koonin, Mart Krupovic
    As long suspected, poxviruses capture host genes through a reverse-transcription process now shown to be mediated by retrotransposons.
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    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Neurotransmission: Unmasking a two-faced protein

    Ivan Maslov, Jelle Hendrix
    Single-molecule fluorescence spectroscopy and molecular dynamics simulations illuminate the structure and dynamics of PSD-95, a protein involved in neural plasticity.
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    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Heterochromatin: More than just an inert dense region

    Abdou Akkouche, Emilie Brasset
    A newly discovered protein helps define a subset of heterochromatin regions that can silence harmful mobile genetic elements in the genome of fruit flies.
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    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Histones: A new route to the nucleus

    Hongyu Bao, Hongda Huang
    A newly discovered pathway suggests histone proteins H3 and H4 are imported into the nucleus as individual units rather than joined together as heterodimers as was previously thought.
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    1. Evolutionary Biology

    Cave Bacteria: Illuminating a new path to multicellularity

    Sayantan Datta, William C Ratcliff
    A new species of multicellular bacteria broadens our understanding of prokaryotic multicellularity and provides insight into how multicellular organisms arise.
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