Johannes Felix Stortz, Mario Del Rosario ... Sujaan Das
Formin-2 controls spatiotemporal polymerisation of actin filaments, a common mechanism used by apicomplexans for effective segregation of essential chloroplast-like organelles called apicoplasts, and additionally for daughter formation in Plasmodium falciparum.
Patrick J Karas, John F Magnotti ... Michael S Beauchamp
Human perception and brain responses differ between words, in which mouth movements are visible before the voice is heard, and words, for which the reverse is true.
Jacob LS Bellmund, Lorena Deuker, Christian F Doeller
Mnemonic representations in the human anterior-lateral entorhinal cortex change through learning to reflect an experienced temporal event structure and holistic temporal maps relate to memory recall.
Mahmoud M Elguindy, Florian Kopp ... Joshua T Mendell
Interaction with PUMILIO is essential for maintenance of genomic stability by the cytoplasmic long noncoding RNA NORAD, whereas binding to RBMX is dispensable for this function.
Pierre-Yves Musso, Pierre Junca ... Michael D Gordon
The Sip-Triggered Optogenetic Behavior Enclosure (STROBE) produces robust behaviors via activation of peripheral or central neurons in the fly, and mimics key features of feeding driven by chemical taste ligands.
The activity of serotonergic neurons spanning multiple olfactory areas is regulated by both local synaptic interactions and dendrite wide computations.
Ben F Brian IV, Adrienne S Jolicoeur ... Tanya S Freedman
The ubiquitin ligase c-Cbl preferentially targets unique-region phosphorylated LynA for rapid degradation, regulating its expression and differentially tuning signaling responsiveness in macrophages and mast cells.
Multiple enhancers in physical proximity can reinforce shared transcriptional 'hubs' to preserve their transcriptional output, providing a buffer during environmental stresses and genetic perturbations to preserve phenotypic robustness.
In multi-channel sensory systems, gain adaptation can help maintain not only coding capacity across changes in signal intensity, but also combinatorial representations of odor identity.
