Igor Y Iskusnykh, Nikolai Fattakhov ... Victor V Chizhikov
LIM-homeodomain transcription factor Lmx1a co-regulates multiple developmental processes in the cortical hem, a major signaling center necessary for hippocampus formation in the mammalian brain.
Identification of human DNA sites differentially methylated with aging across six different primary immune cells suggests that the sensing of hypoxia drives the epigenetic clock.
Sydney M Bailes, Daniel EP Gomez ... Laura D Lewis
The frequency content of resting-state fMRI signals contains information that can characterize and predict local variations in hemodynamic response timing which enhances the temporal precision of fMRI.
Genome-scale integration of transposon mutagenesis with a redox biosensor identified a hypothetical transcription factor- Rv0158 required to calibrate the growth, cytoplasmic redox potential, and respiration of Mycobacterium tuberculosis in response to metabolic switching from glucose to fatty acids.
Characterization of an extra-membrane site in IKs formed by KCNQ1 S1, Pore and S6 domains and the near extracellular region of KCNE1, which forms a binding pocket for channel activators.
A new fossil sheds light on the evolution of an aquatic lifestyle in extinct reptiles and supports a close phylogenetic relationship between archosaurs (crocodiles, dinosaurs, birds, and kin) and turtles.
Xinle Zou, Sri Karthika Shanmugam ... Henry M Colecraft
Targeted recruitment of protein kinase A subunits enables distinctive regulation of the functional expression of a potassium channel depending on whether the enzyme is targeted to a pore-forming or auxiliary subunit.
A near-linear relationship between electrical stimulus duration and resultant joint torque in stick insects has been unveiled, enhancing control strategies in biohybrid robotics.