Browse our Research Articles

Page 423 of 1,394
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses

    Manutea C Serrero, Virginie Girault ... Beate Sodeik
    Novel cell-free biochemical experiments show that the host GTPase MxB can restrict the infection of alphaherpesviruses by disassembling the sturdy viral capsids so that they can no longer protect the viral genomes.
    1. Neuroscience

    Imaging of the pial arterial vasculature of the human brain in vivo using high-resolution 7T time-of-flight angiography

    Saskia Bollmann, Hendrik Mattern ... Jonathan R Polimeni
    Partial-volume effects were found to be the current limit to imaging pial arteries with MRI, not their slow blood flow, and therefore advanced acquisition techniques achieving resolutions below 200 µm in vivo provide a more complete picture of these vessels.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Constitutive loss of DNMT3A causes morbid obesity through misregulation of adipogenesis

    Ayala Tovy, Jaime M Reyes ... Margaret A Goodell
    Normal adipogenesis requires de novo DNA methyltransferase 3A (DNMT3A) for proper differentiation and suppression of an age-associated pathogenic inflammatory program.
    1. Neuroscience

    Invariant representation of physical stability in the human brain

    RT Pramod, Michael A Cohen ... Nancy Kanwisher
    Scenario-invariant representation of physical stability is found in the frontoparietal regions but not the ventral visual pathway (and ImageNet-trained convolutional neural networks), consistent with the hypothesis that computations underlying physical stability may entail forward simulations of what will happen next.
    1. Microbiology and Infectious Disease

    Typhoid toxin sorting and exocytic transport from Salmonella Typhi-infected cells

    Shu-Jung Chang, Yu-Ting Hsu ... Jorge E Galan
    A multidisciplinary approach provides a description of the exocytic pathway that exports Salmonella Typhi's typhoid toxin from infected cells.
    1. Neuroscience

    A tonic nicotinic brake controls spike timing in striatal spiny projection neurons

    Lior Matityahu, Jeffrey M Malgady ... Joshua L Plotkin
    A novel mechanism describes how tonic activation of nicotinic acetylcholine receptors can modulate the timing of striatal output by priming feedforward inhibition.
    1. Cell Biology
    2. Immunology and Inflammation

    A B-cell actomyosin arc network couples integrin co-stimulation to mechanical force-dependent immune synapse formation

    Jia C Wang, Yang-In Yim ... John A Hammer
    B-cell integrin co-stimulation promotes the formation of an actomyosin network that drives integrin-dependent immune synapse formation and B-cell activation.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Radiocarbon and genomic evidence for the survival of Equus Sussemionus until the late Holocene

    Dawei Cai, Siqi Zhu ... Yu Jiang
    The first nuclear genomes of the Equus (Sussemionus) ovodovi enable us to reconstruct the speciation and extinction trajectory of this lineage.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells

    Le Xiong, Erik A Tolen ... Hans R Schöler
    Time-resolved multiomics analysis during Oct4 depletion and recovery reveals concentration-dependent activities of Oct4 in controlling enhancer transcription and chromatin accessibility in mouse embryonic stem cells.
    1. Ecology
    2. Neuroscience

    Unique neural coding of crucial versus irrelevant plant odors in a hawkmoth

    Sonja Bisch-Knaden, Michelle A Rafter ... Bill S Hansson
    The sense of smell of female hawkmoths has evolved to find the intense odor of floral nectar sources as well as inconspicuous scents of oviposition sites within a complex olfactory landscape.