Browse our Research Articles

Page 53 of 1,446
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Myosin light chain 3 serves as a receptor for nervous necrosis virus entry into host cells via the macropinocytosis pathway

    Lan Yao, Wanwan Zhang ... Kuntong Jia
    MYL3 is identified as a novel receptor enabling nervous necrosis virus (NNV) entry via macropinocytosis, revealing a therapeutic target for combating NNV outbreaks in aquaculture.
    1. Neuroscience

    Investigating working memory updating processes of the human subcortex using 7T MRI

    Anne C Trutti, Zsuzsika Sjoerds ... Birte U Forstmann
    Neuroimaging evidence enhances understanding of the subcortex’s role in the neural mechanisms of working memory updating, providing new insights into midbrain function.
    1. Structural Biology and Molecular Biophysics

    LC8 enhances 53BP1 foci through heterogeneous bridging of 53BP1 oligomers

    Jesse Howe, Douglas Walker ... Elisar J Barbar
    The oligomerization domain of 53BP1, a key DNA repair protein, is a trimer which binds the dimeric hub protein LC8 by a novel mechanism to form dynamic heterogeneous complexes.
    1. Neuroscience

    Striatal cholinergic interneuron pause response requires Kv1 channels, is absent in dyskinetic mice, and is restored by dopamine D5 receptor inverse agonism

    Cecilia Tubert, Rodrigo Manuel Paz ... Mario Gustavo Murer
    Restoring the Kv1-mediated pause in striatal cholinergic interneurons by reducing D5 receptor activity may help recover striatal function lost in dyskinetic parkinsonian mice.
    1. Neuroscience

    Neural dynamics of visual working memory representation during sensory distraction

    Jonas Karolis Degutis, Simon Weber ... John-Dylan Haynes
    Dynamic shifts in neural coding combined with stable population subspaces enable visual areas to concurrently represent sensory inputs and working memory without mutual interference.
    1. Neuroscience

    Distinct neural bases of subcomponents of the attentional blink

    Swagata Halder, Deepak Velgapuni Raya, Devarajan Sridharan
    The attentional blink selectively impairs one component of attention, and impacts both target detection and discrimination via separable neural signatures.
    1. Neuroscience

    Sigh generation in preBötzinger complex

    Yan Cui, Evgeny Bondarenko ... Jack L Feldman
    Activation of NMB/GRP receptors is not necessary for sigh generation, while SST preBötC neurons are critical for generation of sighs.
    1. Cell Biology

    The triad interaction of ULK1, ATG13, and FIP200 is required for ULK complex formation and autophagy

    Yutaro Hama, Yuko Fujioka ... Nobuo N Noda
    AlphaFold-guided in vitro and in vivo analyses establish the mechanism of ULK complex formation and provide a structural basis for understanding its role in mammalian autophagy initiation.
    1. Cell Biology

    Nonequilibrium polysome dynamics promote chromosome segregation and its coupling to cell growth in Escherichia coli

    Alexandros Papagiannakis, Qiwei Yu ... Christine Jacobs-Wagner
    Polysome formation within the nucleoid and repulsion between these major cytoplasmic components provide a self-organizing mechanism for chromosome segregation and modulation of its timing across growth rates in Escherichia coli.
    1. Immunology and Inflammation

    Hypothermia protects against ventilator-induced lung injury by limiting IL-1β release and NETs formation

    Nobuyuki Nosaka, Vanessa Borges ... Kenichi Shimada
    Therapeutic hypothermia mitigates ventilator-induced lung injury by suppressing macrophage-derived IL-1β release, thereby reducing neutrophil extracellular trap formation, vascular leakage, and hypoxemia in a two-hit acute lung injury model.