B-type natriuretic peptide (BNP) modulates itch via BNP-NPRC pathway by enhancing NMB-NMBR signaling, which is independently of gastrin-releasing peptide (GRP)-GRPR signaling in the spinal cord.
Nikos Stratakis, Alexandros P Siskos ... Leda Chatzi
Urinary metabolic signatures relate to adherence to the Mediterranean diet and ultra-processed food intake in childhood and reflect associations of these diet quality indicators with metabolic health.
Personalized virtual-heart technology for arrhythmia risk assessment could transform the management of hypertrophic cardiomyopathy patients, eliminating many unnecessary primary-prevention defibrillator deployments while ensuring patients at high risk for arrhythmia are adequately protected.
Susan Martin, Jessica Tyrrell ... Hanieh Yaghootkar
Using genetics, it is possible to uncouple higher adiposity from its adverse metabolic effects and show that some obesity-associated conditions may benefit from treating the metabolic effects alone, whilst others may benefit more from weight loss.
Giacomo Ariani, J Andrew Pruszynski, Jörn Diedrichsen
Movement planning elicits finger-specific activity in primary somatosensory cortex that is strongly correlated to the finger-specific activity elicited during movement execution.
The cargo adapter ARMC2 mediates the association of radial spoke complexes to IFT trains ensuring radial spoke import and assembly in Chlamydomonas flagella.
Archerfish (Toxotes jaculatrix) can encode an abstract concept of number in relative numerousness judgements, without the influence of any continuous physical variables, including spatial frequency.