Subthalamic nucleus spiking activity, beta oscillation power, and locking of spikes to the beta oscillation are decreased prior to changes in ongoing movements.
Emily R Ebel, Frans A Kuypers ... Elizabeth S Egan
Human red blood cells from healthy donors display marked biophysical and genetic variation that impacts the growth of Plasmodium falciparum malaria parasites, outside of known disease alleles.
Katherine B LeClair, Kenny L Chan ... Scott J Russo
Socially dominant mice, unlike subordinates, are protected from displaying a common stress-associated behavioral deficit, social avoidance, following exposure to multiple kinds of chronic stress.
A trait-based model of dryland vegetation uncovers the roles of spatial self-organization in maintaining biodiversity in a changing climate and offers novel ways of managing ecosystems at risk.
The small ubiquitin-like modifier system directly regulates components of the chloroplast protein import apparatus, that is, TOC proteins, to control chloroplast biogenesis and plant development.
Isabella Farhy-Tselnicker, Matthew M Boisvert ... Nicola J Allen
RNA sequencing and genetic mouse models reveal that transcriptional changes to astrocytes in the developing cortex are not intrinsic but influenced by their environment and determine that expression of astrocyte synapse-regulating genes and neuronal synaptogenesis is modulated by ongoing astrocyte-neuron communication.
Convergent structural and functional brain deficits associated with dyslexia were found in left superior temporal gyrus across languages, however, language-specific deficits were also identified.
Luca Tirinato, Maria Grazia Marafioti ... Joao Seco
Lipid Droplet accumulation is a fingerprint shared by different human cancer radioresistant cells and their biogenesis strongly depend on FTH1 presence.
Certain mutational signatures vary in their contribution to genetic variation across the yeast phylogeny due to genetically encoded natural mutator phenotypes whose activity can be directly measured in the lab.
High-throughput and ultra-stable magnetic tweezers reveal that Remdesivir induces a long-lived backtrack pause upon incorporation by the coronavirus polymerase, and SARS-CoV-2 is able to evade interferon-induced antiviral ddhCTP.
