Browse our Research Articles

Mutating a highly conserved intramembrane salt bridge unmasks structural and functional coupling between channel gating and ion permeation in the muscle nicotinic receptor.

A comparison of different computational models reveals that looking behavior, during value-based choices from 9, 16, 25, or 36 snack foods, actively influences the subjective values of the available alternatives.

A human experimental model for physiological glucocorticoid exposure and glucocorticoid withdrawal identifies a multi-omic cluster, including microRNA miR-122-5p and metabolites, associated with glucocorticoid-responsive genes.

Modifying membrane potential by an 'inhibitory' chloride conductance such as PSAM⁴-GlyR is inherently unstable because the normally low intracellular concentration of chloride is readily increased by influx of chloride.

Elucidating the control and regulation of acetate overflow in E. coli reveals that acetate is not only an end-product but also a co-substrate and a global regulator of glucose metabolism.

Lumen extension in intracellular tubes relies on a molecular pathway involving Rho GTPase signaling, cell polarity, and vesicle-tethering proteins.

Various types of stress reset heritable small RNA responses through the function of the p38 MAPK pathway, the transcription factor SKN-1/Nrf2, and the MET-2/SETDB1 putative histone methyltransferase.

A single-cell atlas of the developing Drosophila wing disc at two time points enables a detailed understanding of the signals exchanged between different cell populations during development.

3D reconstruction for an insect provides new internal structures at nanometer resolution, and the reconstructed feeding insect reveals unexpected contraction of stylet protractors and suggested a novel phloem sap-sucking model.

Chronic alcohol exposure results in a long-lasting, enhanced endocannabinoid signalling at orbitostriatal synapses that is expressed in a projection-, synapse-, and behaviorally computation-specific manner.