Jon C Emery, Timothy W Russell ... Rein MGJ Houben
Nearly 75% of SARS-CoV-2 infections on the Diamond Princess were asymptomatic, half were never detected, and asymptomatic infections may have contributed substantially to transmission.
Amanda M Pocratsky, Courtney T Shepard ... David SK Magnuson
Conditional silencing of long ascending propriospinal neurons disrupts interlimb coordination of the fore and hindlimb pairs, but in a highly context-specific manner.
Mathieu Tremblay, Sophie Viala ... Maxime Bouchard
Gata3 loss in prostate basal stem/progenitor cells upregulates BMP5 which is necessary and sufficient to sustain full self-renewal potential and its inhibition significantly delays both prostate and skin tumor progression.
Clytia jellyfish regenerate body shape and organs through a mechanically driven process that coordinates tissue remodeling, localized proliferation, and precursor migration and promotes Wnt signaling at a muscle-based landmark.
Sean Edward Cavanagh, Norman H Lam ... Steven Wayne Kennerley
Ketamine, an NMDA receptor antagonist and experimental model for schizophrenia, produces decision-making deficits in monkeys, which are predicted by a lowering of cortical excitation-inhibition balance in a spiking circuit model.
Andreas Hoehne, Maureen H McFadden, David A DiGregorio
Transient recruitment of electrical synapses mediates precisely timed excitation and inhibition to enhance synchronized control of cerebellar cortical output.
Lateral gene transfer is unable to resist mutation accumulation in large genomes, leading to selective pressure for the origin of meiotic sex in the first eukaryotes.
Giulia LM Boezio, Anabela Bensimon-Brito ... Didier YR Stainier
Alk5/TGF-β signaling is required in the endothelium to orchestrate zebrafish cardiac outflow tract morphogenesis, regulating smooth muscle cell and extracellular matrix organization.
Women with unexplained miscarriages have an altered behavioral and brain response to men's body-odor, and this may reflect a factor in their condition.