A single-cell RNA sequencing reveals cell heterogeneity of secondary metabolism in tea plant root and a proposed model in which the theanine biosynthesis pathway occurs via multicellular compartmentation.
Cell-cell interaction between neural crest-derived cells and mesoderm-derived cells determine cell fate of mesoderm-derived cell in tongue development through Hh signaling.
Whole-brain light-sheet imaging of axons segmented by trained convolutional networks reveals distinct projection patterns of genetically defined classes of neurons in primary and secondary whisker-related somatosensory cortices.
The newly developed antibody-free techniques, HepG4-seq for G-quadruplexes and HBD-seq for R-loops, robustly reveal the comprehensive maps of native G-quadruplexes and R-loops, as well as their roles in transcriptional regulation.
Genetic, cellular, and molecular analyses reveal that the reduced abundance of total nascent transcripts that occurs after irradiation is largely due to the repression of histone and rRNA encoding genes.
A new online data analysis platform, Mendelian Randomization for Alzheimer’s Disease (MRAD), enables the identification of risk or protective factors for Alzheimer’s disease.
Resting natural killer cells promote the progress of colon cancer liver metastasis (CCLM), which may be exploited for novel strategies to improve therapeutic outcomes for patients with CCLM.
Nanopore sequencing effectively resolves key challenges in bacterial small variant detection, providing a more accurate alternative to traditional sequencing methods.
Brain ventricular astrogliosis and neuroinflammation precede scoliosis onset in the zebrafish rpgrip1l ciliary mutant and anti-inflammatory treatment drastically reduces scoliosis while correcting urotensin related peptide level is ineffective.
