The Marmoset Apparatus for Automated Pulling provides a powerful and scalable experimental platform for studying behavioral and neural mechanisms underlying cooperation in freely moving marmosets.
Thi Mong Quynh Pham, Thanh Nhan Nguyen ... Le Son Tran
The integration of pHLA binding and pHLA-TCR analysis effectively improves the precision of insilico neoantigen prioritization, potentially enhancing personalized immunotherapies for colorectal cancer.
Miguel Martinez-Ara, Federico Comoglio, Bas van Steensel
A high-throughput enhancer-enhancer-promoter reporter assay indicates that pairs of enhancers generally activate promoters in a near-additive manner, and that promoters transform their collective effect non-linearly.
Valentina Stolz, Rafael de Freitas e Silva ... Wilfried Ellmeier
The transcriptional adapter protein NCOR1 that links chromatin-modifying enzymes with gene-specific transcription factors controls naive and effector regulatory T cell states.
Distinct local dynamics of different hypothalamus areas were detected in response to changing illuminance and could contribute to light’s impact on cognition.
Nathaniel Paul Meyer, Tania Singh ... Diane L Barber
Clonal naïve human embryonic stem cells assemble an Arp2/3 complex-dependent contractile actin filament ring around colonies that promotes tensional forces favoring cell-cell adhesion and nuclear translocation of YAP to maintain ground-state pluripotency.
Modulation of division plane rotation in proliferating chondrocytes determines the ratio of clusters and columns, which may support the multifunctional design of the growth plate.
