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    1. Neuroscience

    A dynamic generative model can extract interpretable oscillatory components from multichannel neurophysiological recordings

    Proloy Das, Mingjian He, Patrick L Purdon
    Oscillation component analysis enables cognitive neuroscientists to summarize millisecond-precision high-dimensional neurophysiological recordings into a smaller set of oscillatory components through biophysically inspired generative modeling of neural oscillations.
    1. Biochemistry and Chemical Biology

    Probing PAC1 receptor activation across species with an engineered sensor

    Reto B Cola, Salome N Niethammer ... Tommaso Patriarchi
    A new genetically encoded sensor robustly detects exogenously applied PAC1R ligands in vitro, ex vivo, and in vivo (in zebrafishes and mice) serving as a useful resource for probing PAC1R functions.
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    OpenNucleome for high-resolution nuclear structural and dynamical modeling

    Zhuohan Lao, Kartik D Kamat ... Bin Zhang
    An open-source tool for computational simulations of the human genome has been introduced, enabling the characterization of complex nuclear environments and the interpretation of experimental observations.
    1. Cancer Biology

    RGS10 deficiency facilitates distant metastasis by inducing epithelial–mesenchymal transition in breast cancer

    Yang Liu, Yi Jiang ... Xi Gu
    The novel action of RGS10 in epithelial–mesenchymal transition in breast cancer is dependent on LNC2 and miR-539-5p, which is identified as a prognostic biomarker for early distant metastasis in breast cancer.
    1. Cell Biology
    2. Neuroscience

    Plasticity-induced actin polymerization in the dendritic shaft regulates intracellular AMPA receptor trafficking

    Victor C Wong, Patrick R Houlihan ... Erin K O'Shea
    Glutamate receptor-containing vesicles are positioned in the dendritic shaft near sites of synaptic activity by F-actin.
    1. Neuroscience

    Semantic plasticity across timescales in the human brain

    Sarah H Solomon, Kendrick Kay, Anna C Schapiro
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry

    Wei Q Deng, Nathan Cawte ... Sonia S Anand
    Epigenetic signature of maternal smoking contributes to smaller body size and lower birth weight in newborns of European and South Asian ancestry.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Observing one-divalent-metal-ion-dependent and histidine-promoted His-Me family I-PpoI nuclease catalysis in crystallo

    Caleb Chang, Grace Zhou, Yang Gao
    In crystallo observation of HNH family I-PpoI nuclease cleaving DNA suggests that one divalent metal ion and a histidine are required for catalysis.
    1. Neuroscience

    A scene with an invisible wall - navigational experience shapes visual scene representation

    Shi Pui Donald Li, Jiayu Shao ... Soojin Park
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Stimulus-specificity of surround-induced responses in primary visual cortex

    Nisa Cuevas, Boris Sotomayor-Gómez ... Martin Vinck
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete