Browse the latest research

Single-cell RNA sequencing analysis of diabetic mouse cavernous tissue revealed that LBH is a novel pericyte marker and may interact with Crystallin Alpha B and Vimentin to promote neurovascular regeneration.

A novel bilinear modeling approach reveals genetic code of neuronal connectivity, offering insights for targeted genetic interventions in neural circuits.

Disrupted mesenchymal Bmpr1a-mediated signaling in fetal mouse lung leads to abnormal airway development and congenital pulmonary cyst formation.

LRRK plays an essential, cell-intrinsic role in the protection of dopaminergic neurons during aging, and new genetic findings suggest that LRRK2 mutations may impair its function, leading to dopaminergic neurodegeneration in PD.

The peptidoglycan hydrolase activity of Enterococcus faecium secreted antigen A is crucial for cell wall remodeling during bacterial cell separation and generates muropeptides that stimulate host immunity to enhance immune checkpoint inhibitor anti-cancer therapy.

A novel targeted protein degradation system to achieve cell-type-specific enhancement of Wnt signaling.

Facultative parthenogenesis in whiptail lizards produces genome-wide homozygosity in offspring.

Strategic pegRNA designs and other approaches mitigating 5' and 3' interactions within pegRNAs can often lead to substantial improvements in prime editing efficiency.