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Abundant mitochondrial DNA of long-extinct large mammals in recent sediment of Siberian lakes suggests complex taphonomic redistribution.

Gut microbiota-derived gamma-aminobutyric acid is identified as a key metabolite that metformin protect from hepatic ischemia/reperfusion injury.

Open-top Bessel beam two-photon light sheet microscopy have the potential for rapid and accurate nondestructive pathology by visualizing 3D histological information.

Length-dependent interference of arginine-containing dipeptide repeat proteins with multiple components of the nucleocytoplasmic transport machinery is a potential mechanistic pathway of C9orf72 amyotrophic lateral sclerosis or frontotemporal dementia toxicity.

Cell and animal-based models revealed the new function of TLR2 andcarboxyethylpyrrole as an endogenous TLR2 ligand in the hair follicle cycle in homeostasis and hair follicle regeneration in injury.

The promising potential of plasma extracellular vesicle synaptic proteins as clinical biomarkers of disease progression in Parkinson's disease has been presented.

Rbm24 is controlled by Pou4f3 but not Gfi1 during cochlear hair cell development.

SNP-editing of human embryonic stem cells reveals cell type specific function of a genetic variant associated with changes in human jaw shape.