Jessica Gray, Von Vergel L Torres ... Ian R Henderson
Klebsiella pneumoniae has specific repertoires of genes required for growth in urine and serum, highlighting new targets for antimicrobial treatments of this important pathogen.
Long-term physical exercise had a substantial effect on the plasma proteome, identifying novel exerkines and suggesting CD300LG as a potential link to insulin sensitivity.
Benjamin R Kop, Yazan Shamli Oghli ... Lennart Verhagen
Realizing the clinical and neuroscientific potential of transcranial ultrasonic stimulation (TUS) requires careful control of the peripheral auditory confounds that underlie previously reported online motor inhibitory effects.
The hypo- versus hyperkinetic nature of Parkinson’s disease and dystonia, respectively, may be reflected by differences in disease-specific spiketrain dynamics and striato-pallidal synaptic plasticity.
Teresa Attenborough, Kate A Rawlinson ... Matthew Berriman
A comprehensive description of gene expression and organisation in the cells that constitute the blood fluke larvae responsible for finding and invading its intermediate host.
Analyses of epigenetic profiles using ATAC-seq provide a comprehensive investigation of the chromatin landscape in hampered GABAergic differentiation in a DS-patient iPSC-derived disease model.
Changes in the amount and timing of gene expression during early development contribute to evolutionary divergence and life-history changes, even within a species.
MYCN and TFIIIC exert a censoring function during early transcription, limiting the accumulation of inactive RNAPII at the promoter and facilitating promoter-proximal degradation of nascent RNA.
