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Page 306 of 1,780
    1. Neuroscience

    Indistinguishable network dynamics can emerge from unalike plasticity rules

    Poornima Ramesh, Basile Confavreux ... Jakob H. Macke
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Microbiology and Infectious Disease

    Un1Cas12f1 and Cas9 gene drive in HSV1: viruses that ‘infect’ viruses

    Qiaorui Yao, Zhuangjie Lin ... Hongsheng Dai
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Noradrenaline release from the locus coeruleus shapes stress-induced hippocampal gene expression

    Mattia Privitera, Lukas M von Ziegler ... Johannes Bohacek
    Targeted manipulation of the locus coeruleus noradrenaline circuitry combined with extensive transcriptomic analyses in the mouse hippocampus reveal a unique set of noradrenaline-dependent, stress-related genes and point to astrocytic engagement.
    1. Neuroscience

    Causal role of the frontal eye field in attention-induced ocular dominance plasticity

    Fangxing Song, Xue Dong ... Min Bao
    A series of experiments suggest that the fronto-parietal attentional network is involved in controlling eye-based attention, and FEF plays a crucial causal role in generating the attention-induced ocular dominance shift.
    1. Neuroscience

    Structural constraints on the emergence of oscillations in multi-population neural networks

    Jie Zang, Shenquan Liu ... Arvind Kumar
    An odd number of inhibitory links in a network are necessary and sufficient to make a network of neuron populations oscillate.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Gene expression plasticity followed by genetic change during colonization in a high-elevation environment

    Huishang She, Yan Hao ... Yanhua Qu
    An integrative approach allows investigations of the relationship between an initial plasticity and the subsequent adaptive evolution during rapid adaptive modification of complex systems in the wild.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    The catalytic mechanism of the RNA methyltransferase METTL3

    Ivan Corbeski, Pablo Andrés Vargas-Rosales ... Amedeo Caflisch
    A multidisciplinary study reveals the reaction mechanism and transition state of adenosine-N6 methyl transfer catalyzed by human METTL3-14, deepening our insight into RNA methyltransferases and paving the way for similar studies on related enzymes.
    1. Developmental Biology

    FBXO24 modulates mRNA alternative splicing and MIWI degradation and is required for normal sperm formation and male fertility

    Zhiming Li, Xingping Liu ... Shuiqiao Yuan
    Animal models and molecular data reveal how FBXO24 regulates mRNA expression and MIWI degradation in the round spermatids.