Browse the latest research

Page 454 of 1,892
    1. Neuroscience

    Multiple NTS neuron populations cumulatively suppress food intake

    Weiwei Qiu, Chelsea R Hutch ... Darleen Sandoval
    Analyses reveal that multiple NTS neuron types act cumulatively in the suppression of feeding, that the abrogation of food intake by multiple non-aversive populations fails to promote aversive responses, and that there exist additional NTS populations that modulate food intake.
    1. Cancer Biology

    Disseminating cells in human oral tumours possess an EMT cancer stem cell marker profile that is predictive of metastasis in image-based machine learning

    Gehad Youssef, Luke Gammon ... Adrian Biddle
    Cancer stem cells that have undergone EMT are identified in the region surrounding metastatic human oral tumours in a retrospective cohort study, and these are predictive of metastatic outcome in an image-based machine learning approach.
    1. Neuroscience

    Early roots of information-seeking: Infants predict and generalize the value of information

    Tommaso Ghilardi, Francesco Poli ... Sabine Hunnius
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology

    Gcn5 – mTORC1 – TFEB signalling axis mediated control of autophagy regulates Drosophila blood cell homeostasis

    AR Arjun, Suraj Math ... Rohan Jayant Khadilkar
    Not revised
    Reviewed Preprint v1
    • Solid
    • Inadequate
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Microstructural differences in the osteochondral unit of terrestrial and aquatic mammals

    Irina AD Mancini, Riccardo Levato ... Jos Malda
    Analysis of the osteochondral unit of aquatic mammals reveals a distinctly different tissue structure, lacking the arcade-like collagen fiber organization, a calcified cartilage layer and a dense subchondral bone plate, typically seen in osteochondral tissue of terrestrial mammals.
    1. Neuroscience

    The Na+ leak channel NALCN controls spontaneous activity and mediates synaptic modulation by α2-adrenergic receptors in auditory neurons

    Tenzin Ngodup, Tomohiko Irie ... Laurence O Trussell
    Noradrenergic receptors can control the spontaneous electrical firing of neurons by inhibiting a Na+ channel known as NALCN using a pathway shared by metabotropic GABA receptors.
    1. Neuroscience

    Silencing long-descending inter-enlargement propriospinal neurons improves hindlimb stepping after contusive spinal cord injuries

    Courtney T Shepard, Brandon L Brown ... David SK Magnuson
    Silencing long-descending propriospinal neurons that connect C6 to L2 disrupts right-left alternation of both the forelimbs and hindlimbs in the intact animal, but leads to improved stepping after a mild-moderate thoracic contusion spinal cord injury.
    1. Neuroscience

    A comprehensive neuroanatomical survey of the Drosophila Lobula Plate Tangential Neurons with predictions for their optic flow sensitivity

    Arthur Zhao, Aljoscha Nern ... Michael B. Reiser
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology

    Acyl-CoA thioesterase-2 facilitates β-oxidation in glycolytic skeletal muscle in a lipid supply dependent manner

    Carmen Bekeova, Ji In Han ... Erin L. Seifert
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Evolutionary Biology
    2. Genetics and Genomics

    The genomic footprint of social stratification in admixing American populations

    Alex Mas-Sandoval, Sara Mathieson, Matteo Fumagalli
    Social hierarchies resulting from the European colonization of the Americas stratified the population structure, leading to ancestry-related assortative mating and sex bias patterns that can be inferred from the genomes of the populations across the continent.