Browse the latest research

Page 474 of 1,892
    1. Developmental Biology

    The myocardium utilizes a platelet-derived growth factor receptor alpha (Pdgfra)–phosphoinositide 3-kinase (PI3K) signaling cascade to steer toward the midline during zebrafish heart tube formation

    Rabina Shrestha, Tess McCann ... Joshua Bloomekatz
    Research on heart tube assembly using zebrafish reveals a pivotal role for intrinsic Pdgfra–PI3K signaling in steering the movement of the myocardium and polarizing myocardial cell protrusions.
    1. Neuroscience

    Conscious processing of global and local auditory irregularities causes differentiated heartbeat-evoked responses

    Diego Candia-Rivera, Federico Raimondo ... Jacobo D Sitt
    Brain-heart interactions under the processing of auditory irregularities could help to distinguish whether a patient is in a vegetative state or in a minimally conscious state.
    1. Neuroscience

    Combined transcranial magnetic stimulation and electroencephalography reveals alterations in cortical excitability during pain

    Nahian Shahmat Chowdhury, Alan KI Chiang ... Siobhan M Schabrun
    Combined TMS-EEG can be used to further elucidate the mechanisms for pain perception and to discover biomarkers for the development of chronic pain.
    1. Ecology
    2. Evolutionary Biology

    miR-252 targeting temperature receptor CcTRPM to mediate the transition from summer-form to winter-form of Cacopsylla chinensis

    Songdou Zhang, Jianying Li ... Xiaoxia Liu
    The first comprehensive study on the regulation mechanism of miR-252 and temperature receptor CcTRPM on insect seasonal polyphenism will also conducive to designing a new method for pest control.
    1. Cancer Biology
    2. Medicine

    Tissue-derived exosome proteomics identifies promising diagnostic biomarkers for esophageal cancer

    Dingyu Rao, Hua Lu ... Zhixian Tang
    Exosomal CD54 can be used as an effective biomarker for esophageal squamous cell carcinoma and CD54 promotes the proliferation and migration of tumor cells in vitro.
    1. Structural Biology and Molecular Biophysics

    Mechanism of substrate binding and transport in BASS transporters

    Patrick Becker, Fiona Naughton ... Alexander D Cameron
    The putative substrate pantoate binds to a sodium-coupled secondary transporter of the bile acid sodium symporter family, with sodium-dependent binding and conformational changes consistent with an elevator mechanism of transport.
    1. Stem Cells and Regenerative Medicine

    Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors

    Lampros Mavrommatis, Hyun-Woo Jeong ... Holm Zaehres
    Skeletal muscle organoids differentiated from human pluripotent stem cells offer a system for investigating myogenesis and satellite cell development with translational potential for muscular dystrophy modeling and therapy development.
    1. Neuroscience

    Cue- versus reward-encoding basolateral amygdala projections to nucleus accumbens

    Yi He, Yanhua H Huang ... Yan Dong
    Two distinct projections from the basolateral amygdala to nucleus accumbens differentially contribute to cue- versus reward-mediated behavioral reinforcement.
    1. Neuroscience

    Mesotrode allows chronic simultaneous mesoscale cortical imaging and subcortical or peripheral nerve spiking activity recording in mice

    Dongsheng Xiao, Yuhao Yan, Timothy H Murphy
    Low-profile tetrodes that are compatible with wide-field imaging provide the opportunity to evaluate the relationship between spiking neurons and broad networks.