Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cancer Biology
    2. Cell Biology

    mTORC1/S6K1 signaling promotes sustained oncogenic translation through modulating CRL3IBTK-mediated ubiquitination of eIF4A1 in cancer cells

    Dongyue Jiao, Huiru Sun ... Kun Gao
    Overexpression of inhibitor of Bruton's tyrosine kinase contributes to the process of tumorigenesis by amplifying translation, represents a promising target for anti-cancer therapies.
    1. Cell Biology

    Genome concentration limits cell growth and modulates proteome composition in Escherichia coli

    Jarno Mäkelä, Alexandros Papagiannakis ... Christine Jacobs-Wagner
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    MEMO1 binds iron and modulates iron homeostasis in cancer cells

    Natalia Dolgova, Eva-Maria E Uhlemann ... Oleg Y Dmitriev
    Cancer metastasis modulator MEMO1 binds iron and is involved in regulating iron homeostasis in cancer cells.
    1. Cell Biology

    Transcriptomic profiling of Schlemm’s canal cells reveals a lymphatic-biased identity and three major cell states

    Revathi Balasubramanian, Krishnakumar Kizhatil ... Simon W.M. John
    1. Cell Biology
    2. Neuroscience

    Sympathetic Motor Neuron Dysfunction is a Missing Link in Age-Associated Sympathetic Overactivity

    Lizbeth de la Cruz, Derek Bui ... Oscar Vivas
    1. Cell Biology

    Pigmentation level of human iPSC-derived RPE does not indicate a specific gene expression profile

    Yoko Nakai-Futatsugi, Jianshi Jin ... Masayo Takahashi
    Pigmentation that confers protective function of RPE is not underlaid by a specific gene expression profile, reviled by microscopic imaging together with single-cell RNA sequencing.
    1. Cancer Biology
    2. Cell Biology

    CYRI-B mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake

    Savvas Nikolaou, Amelie Juin ... Laura M Machesky
    1. Cell Biology
    2. Neuroscience

    Synapsin E-domain is essential for α-synuclein function

    Alexandra Stavsky, Leonardo A Parra-Rivas ... Daniel Gitler
    Alpha-synuclein binding to the synapsin E-domain is essential and sufficient for their cooperation in attenuating synaptic-vesicle trafficking and neurotransmission.

Senior editors

  1. Felix Campelo
    The Institute of Photonic Sciences, Spain
  2. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  3. Adèle L Marston
    University of Edinburgh, United Kingdom
  4. See more editors