62 results found
    1. Computational and Systems Biology
    2. Ecology

    Expanding xylose metabolism in yeast for plant cell wall conversion to biofuels

    Xin Li, Vivian Yaci Yu ... Jamie HD Cate
    Parallel pathways of xylose metabolism identified in fungi that grow on plants can be used in yeast to promote hemicellulose conversion to biofuels.
    1. Genetics and Genomics

    A moonlighting function of a chitin polysaccharide monooxygenase, CWR-1, in Neurospora crassa allorecognition

    Tyler C Detomasi, Adriana M Rico-Ramírez ... N Louise Glass
    Allorecognition in Neurospora crassa requires CWR-1 (cell wall remodeling protein), an essential process that ensures identity of an interconnected fungal syncytial colony and requires the CWR-1 polysaccharide monooxygenase domain, but not its catalytic activity.
    1. Ecology

    Symbiosis: Algae and fungi move from the past to the future

    Paola Bonfante
    The ability of photosynthetic algae to enter the hyphae of a soil fungus could tell us more about the evolution of these species.
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    1. Ecology

    Algal-fungal symbiosis leads to photosynthetic mycelium

    Zhi-Yan Du, Krzysztof Zienkiewicz ... Gregory M Bonito
    The capacity for symbiosis between photosynthetic microalgae and early diverging lineages fungi was demonstrated with microscopy and stable isotope exchange of carbon and nitrogen.
    1. Structural Biology and Molecular Biophysics

    Structural basis of EHEP-mediated offense against phlorotannin-induced defense from brown algae to protect akuBGL activity

    Xiaomei Sun, Yuxin Ye ... Min Yao
    A structural and biochemical study reveals the molecular mechanism of the predator–prey associations of Aplysia kurodai and brown algae (akuBGL–phlorotannin/laminarin–EHEP system), which has high-potential applications in the biotechnology industry.
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells

    Nuria Vilaplana-Lopera, Vincent Cuminetti ... Paloma Garcia
    Interplay between AML and stromal cells can initiate a mechanism involving gap junctions where ROS is transferred from cancer cells to stromal cells which then produce acetate which can in return be absorbed/utilised by the cancer cells.
    1. Cell Biology
    2. Immunology and Inflammation

    Acute exposure to apolipoprotein A1 inhibits macrophage chemotaxis in vitro and monocyte recruitment in vivo

    Asif J Iqbal, Tessa J Barrett ... Edward A Fisher
    Mechanistic insights show how treatment with apoA1 is anti-inflammatory by rapidly disrupting macrophage chemotaxis and monocyte recruitment.
    1. Structural Biology and Molecular Biophysics
    2. Chromosomes and Gene Expression

    Selection of chromosomal DNA libraries using a multiplex CRISPR system

    Owen W Ryan, Jeffrey M Skerker ... Jamie HD Cate
    An optimized CRISPR-Cas9 system enables multiplexed genome engineering for evolving biomolecules and pathways from chromosomally integrated DNA libraries.
    1. Ecology

    Point of View: A transatlantic perspective on 20 emerging issues in biological engineering

    Bonnie C Wintle, Christian R Boehm ... William J Sutherland
    Horizon scanning has been used to identify opportunities and risks presented by 20 emerging issues in the field of biological engineering.
    1. Computational and Systems Biology

    Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria

    Roswitha Dolcemascolo, María Heras-Hernández ... Guillermo Rodrigo
    A mammalian protein with RNA recognition motifs can be used in bacteria to engineer post-transcriptional regulation.

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