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    1. Developmental Biology

    Mitochondria: Powering the formation of alveoli

    Qianjiang Hu, Melanie Königshoff
    Two cell types in the lung need specific numbers and distributions of mitochondria for alveoli to form correctly.
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    Insight
    1. Evolutionary Biology
    2. Neuroscience

    Pyramidal Neurons: Looking for the origins of axons

    Kathleen S Rockland
    Pyramidal neurons with axons that exit from dendrites rather than the cell body itself are relatively common in non-primates, but rare in monkeys and humans.
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    Insight
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Defense Proteins: Exposing the invader

    Avraham N Bayer, Fred L Homa
    A restriction factor induced by interferons blocks the replication of herpesviruses by disassembling the capsid proteins surrounding their genome.
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    Insight
    1. Neuroscience

    Synapses: Dividing communication, at the nanoscale

    Amelia J Ralowicz, Michael B Hoppa
    Fluorescent glutamate sensors shed light on the microscopic organization underlining spontaneous neurotransmission.
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    Insight
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Respiro-Fermentation: To breathe or not to breathe?

    Lauren C Radlinski, Andreas J Bäumler
    Listeria monocytogenes uses respiration to sustain a risky fermentative lifestyle during infection.
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    Insight
    1. Immunology and Inflammation

    Autoimmunity: Redoxing PTPN22 activity

    Magdalena Shumanska, Ivan Bogeski
    The oxidative state of a critical cysteine residue determines the enzymatic activity of a phosphatase involved in T-cell immune responses.
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    Insight
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Machine Learning: Lighting up protein design

    Grzegorz Kudla, Marcin Plech
    Using a neural network to predict how green fluorescent proteins respond to genetic mutations illuminates properties that could help design new proteins.
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    Insight
    1. Biochemistry and Chemical Biology

    Genetic Code: Expanding codon size

    Tarana Siddika, Ilka U Heinemann, Patrick O’Donoghue
    Engineering transfer RNAs to read codons consisting of four bases requires changes in tRNA that go beyond the anticodon sequence.
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    Insight
  1. Episode 80: May 2022

    In this episode, we hear about insulin and the body clock, communication in baboons, the sleep patterns of animals in the wild, a new species of dinosaur, and how Covid antibodies produced in response to vaccines and infection compare.
  2. A gloved hand holding a yellow spark on a grey background

    Ukraine: Holding lectures while the bombs fall

    With the Russian army marching on his home city, a Ukrainian scholar must decide how to respond.