Enterococci faecium encodes unique peptidoglycan composition and remodeling activity that activates host immunity.

During early cortical development, microRNA-128 regulates the homeostasis of neural stem cells by targeting PCM1, a protein that is critical for cell division.

rhPTH(1-34) and dimeric ^R25CPTH(1-34) significantly promoted bone regeneration and titanium implant osseointegration in an osteoporotic beagle model.

MgADP binding to the high-affinity 'consensus' ATPase active site of SUR1 and remodeling of the L0-loop (lasso region) overrides tonic ATP inhibition of KATP channels.

The organization of olfactory projection neurons and their synaptic connectivity with third-order neurons studied along with olfactory responses suggest that the labeled-line design is partially at work in the Drosophila olfactory system.

ST recruitment of STRIPAK facilitates PP2A-mediated dephosphorylation of MAP4K4 and induces cell transformation highlighting that STRIPAK complex plays a key role in defining PP2A specificity and activity.

A pooled mutational scanning approach for 3D chromosome conformation reveals how multiple transcription factors can jointly specify condition-specific genome conformations.

Single-cell data analysis must be guided by an underlying model.

Normalizing Tcf4 expression during early postnatal development improves behavioral outcomes in Pitt-Hopkins syndrome (PTHS) model mice, suggesting that genetic therapies are feasible in individuals with PTHS.

HLA class I-disease associations have been studied for decades; a new approach for investigating the underlying mechanism can overcome past problems with interpretation and help to understand the etiology of human diseases.