3,675 results found
    1. Microbiology and Infectious Disease

    Homeostatic control of cell wall hydrolysis by the WalRK two-component signaling pathway in Bacillus subtilis

    Genevieve S Dobihal, Yannick R Brunet ... David Z Rudner
    Molecular genetic analyses define the first homeostatic control pathway that maintains cell wall remodeling activity during bacterial growth.
    1. Microbiology and Infectious Disease

    Infectious polymorphic toxins delivered by outer membrane exchange discriminate kin in myxobacteria

    Christopher N Vassallo, Pengbo Cao ... Daniel Wall
    Serial cell-to-cell transfer of lipoprotein toxins by outer membrane exchange provides a potent platform for kin discrimination in Myxococcus xanthus.
    1. Structural Biology and Molecular Biophysics

    Structure and dynamics of cholesterol-mediated aquaporin-0 arrays and implications for lipid rafts

    Po-Lin Chiu, Juan D Orjuela ... Thomas Walz
    Electron crystallography and molecular dynamics simulations show that a cholesterol sandwiched in between two neighboring aquaporin-0 tetramers stabilizes the association between the tetramers and thus promotes array formation.
    1. Microbiology and Infectious Disease

    Environmental pH signals the release of monosaccharides from cell wall in coral symbiotic alga

    Yuu Ishii, Hironori Ishii ... Shinichiro Maruyama
    Coral symbiotic alga is capable of degrading the own cell wall components by cellulase-related enzymes and releasing sugars as a simple and autonomous environmental response, even when the host-derived signals are not present.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Class-A penicillin binding proteins do not contribute to cell shape but repair cell-wall defects

    Antoine Vigouroux, Baptiste Cordier ... Sven van Teeffelen
    Class-A penicillin-binding proteins are dispensable for rod-like cell-shape but essential for mechanical integrity by sensing and repairing cell-wall defects locally, as investigated in the model system Escherichia coli.
    1. Biochemistry and Chemical Biology

    Membrane-partitioned cell wall synthesis in mycobacteria

    Alam García-Heredia, Takehiro Kado ... M Sloan Siegrist
    Mycobacteria employ plasma membrane compartments to organize their cell wall synthesis, and the finalized cell wall compartmentalizes the plasma membrane to promote an environment conducive to its own synthesis.
    1. Developmental Biology

    The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling

    Seyed Javad Rasouli, Mohamed El-Brolosy ... Didier Y Stainier
    Endocardial Klf2 regulates cardiomyocyte adhesion and myocardial wall integrity by modulating FGF signaling in zebrafish.
    1. Cancer Biology
    2. Neuroscience

    Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer

    Jeffrey Barr, Austin Walz ... Paola D Vermeer
    Nerve tracing and behavioral studies in tumor-bearing mice together with transcriptional and functional analysis reveal cancer-induced central and peripheral neuronal alterations that influence behavior.
    1. Biochemistry and Chemical Biology
    2. Medicine

    Framework for rapid comparison of extracellular vesicle isolation methods

    Dmitry Ter-Ovanesyan, Maia Norman ... David R Walt
    Measuring surface proteins on extracellular vesicles enables quantitative comparison of different isolation methods and optimization of size exclusion chromatography.
    1. Microbiology and Infectious Disease

    Distinct cytoskeletal proteins define zones of enhanced cell wall synthesis in Helicobacter pylori

    Jennifer A Taylor, Benjamin P Bratton ... Nina R Salama
    The helical bacterium Helicobacter pylori patterns cell wall synthesis using two distinct cytoskeletal proteins, CcmA and MreB, to achieve its characteristic shape.

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