Pluripotent stem cell differentiation provides insight into how neural crest subtypes of distinct axial identity are patterned in human embryos.

A thorough insight into the previously unrecognised role of a critical developmental regulator known as TBXT in influencing the specification of human trunk neural crest cells, the presumed precursors of the childhood tumour neuroblastoma.

Despite evidence of retinal stretching with eye growth, cone photoreceptor sampling density in the foveal center of humans actually increases with eye length.

Single-cell RNA sequencing identifies an adult regional gene expression map in planarian muscle that includes two FGFRL-Wnt circuits controlling head and trunk tissue pattern.

Signaling molecules expressed in overlapping body-wide transcriptional gradients determine central axis positional identity in whole-body regeneration.

Morphologic, molecular, biomechanical and computational analyses show that the specialized extracellular matrix architecture of the umbilical artery contributes to its rapid closure at birth and regulates smooth muscle cell differentiation.

R-spondin3 global haplo-insufficiency or its deletion in pre-osteoblasts lead to gain of bone mass in the appendicular skeleton with no or opposite phenotype in the axial skeleton.

Two cancer related proteins, tyrosine phosphatase PTPRK and ubiquitin ligase ZNRF3, interact to downregulate Wnt receptors, thereby regulating Spemann organizer function during Xenopus development.

Distributed cohesin rings flexibly tether the axial element structure of meiotic chromosomes to the underlying chromatin to readily accommodate ongoing transcription.

Spot-On is an easy-to-use website that makes a rigorous and bias-corrected modeling framework for analysis of single-molecule tracking experiments available to all.