121 results found
    1. Neuroscience

    The role of oxytocin in delay of gratification and flexibility in non-social decision making

    Georgia Eleni Kapetaniou, Matthias A Reinhard ... Alexander Soutschek
    Oxytocin was found to significantly improve non-social decision making in a healthy sample, suggesting a domain-general function of the hormone, in contrast to its previously hypothesized social domain specificity.
    1. Neuroscience

    Optogenetic dissection of basolateral amygdala contributions to intertemporal choice in young and aged rats

    Caesar M Hernandez, Caitlin A Orsini ... Jennifer L Bizon
    Optogenetic approaches in young and aged rats define multiple roles for basolateral amygdala in guiding intertemporal choice, and show that these roles change across the lifespan.
    1. Computational and Systems Biology

    Spectral clustering of risk score trajectories stratifies sepsis patients by clinical outcome and interventions received

    Ran Liu, Joseph L Greenstein ... Raimond L Winslow
    Spectral clustering applied to risk trajectories of sepsis patients discovered four distinct clusters stratified by risk of septic shock, mortality, and treatments received prior to an abrupt physiological transition.
    1. Neuroscience

    Neural dynamics underlying self-control in the primate subthalamic nucleus

    Benjamin Pasquereau, Robert S Turner
    Cost–benefit integration between the desirability of the expected reward and the imposed delay to delivery is supported by STN signals that dynamically combined both reward-related attributes to form a single integrated value estimate along an antero-posterior axis in this nucleus.
    1. Neuroscience

    A process model account of the role of dopamine in intertemporal choice

    Alexander Soutschek, Philippe N Tobler
    Drift diffusion models suggest that dopamine affects dissociable components of the decision process in intertemporal choice, underlining the importance of analyzing the effects of neural interventions with process models.
    1. Chromosomes and Gene Expression

    Combinations of maternal-specific repressive epigenetic marks in the endosperm control seed dormancy

    Hikaru Sato, Juan Santos-González, Claudia Köhler
    Analyses of cell type-specific data show that the maternal alleles of genes related to establishing and breaking seed dormancy are suppressed by different combinations of epigenetic marks in the endosperm of Arabidopsis.
    1. Neuroscience

    Neurogenesis: Delayed gratification in the adult brain

    Gerd Kempermann
    Some immature neurons in the cerebral cortex of mammals might wait for years before they become activated and finish their development.
    Version of Record
    Insight
    1. Neuroscience

    Testicular hormones mediate robust sex differences in impulsive choice in rats

    Caesar M Hernandez, Caitlin Orsini ... Jennifer L Bizon
    Sex differences in impulsive decision making, such that males are less impulsive than females, are critically dependent upon testicular but not ovarian hormones.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Estimation and worldwide monitoring of the effective reproductive number of SARS-CoV-2

    Jana S Huisman, Jérémie Scire ... Tanja Stadler
    A new and throughly validated method for timely estimation of the effective reproductive number of SARS-CoV-2 aided in the public health response to the COVID-19 pandemic.
    1. Cancer Biology
    2. Cell Biology

    The cJUN NH2-terminal kinase (JNK) signaling pathway promotes genome stability and prevents tumor initiation

    Nomeda Girnius, Yvonne JK Edwards ... Roger J Davis
    Mutational inactivation of the JNK signaling pathway causes genomic instability and breast cancer development.

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