KLK10 is a flow-sensitive endothelial protein that serves as an anti-inflammatory, barrier-protective, and anti-atherogenic factor with therapeutic potential.
We are writing to respond to the comment by Matthews and Larcombe, 2022 on our article about the life cycle of Trypanosoma brucei (Schuster et al., 2021).
Fluorescent protein-based reporter mouse models revealed that thymic cooperative antigen transfer is mediated by preferential pairing between a particular thymic epithelial cell subset and specific subset(s) of thymic dendritic cells.
Elizabeth J Lawrence, Goker Arpag ... Marija Zanic
SSNA1 is a potent microtubule stabilizer and novel sensor of microtubule damage, acting on both microtubule ends and lattices to regulate microtubule dynamics and protect microtubules against severing activity.
The metal-dependent protein phosphatase Nilkantha, a Drosophila PPM1A/B homolog, dephosphorylates Acinus thereby restraining starvation-independent autophagy.
METTL3 and m6A modifications could alleviate endothelial activation and atherogenesis through accelerated degradation of oscillatory flow-induced EGFR mRNA expression.
Lindsay B Case, Milagros De Pasquale ... Michael K Rosen
Biochemical and cell biological data suggest a model of nascent integrin adhesion complex formation based on synergistic phase separation of pathways surrounding the focal adhesion kinase (FAK) and the adaptor protein p130Cas.