Browse our latest Cell Biology articles

Page 125 of 318
    1. Cell Biology
    2. Neuroscience

    The cryptic gonadotropin-releasing hormone neuronal system of human basal ganglia

    Katalin Skrapits, Miklós Sárvári ... Erik Hrabovszky
    Neuroanatomical studies reveal presence and cholinergic phenotype of 150,000-200,000 extrahypothalamic gonadotropin-releasing hormone neurons in human basal ganglia and basal forebrain, and RNA-sequencing detects gonadotropin-releasing hormone receptor-1 expression in cholinergic interneurons but not in spiny projection neurons of the human putamen.
    1. Cell Biology
    2. Developmental Biology

    Apical PAR complex proteins protect against programmed epithelial assaults to create a continuous and functional intestinal lumen

    Maria Danielle Sallee, Melissa A Pickett, Jessica L Feldman
    During intestinal development, apical PAR complex proteins keep apical domains and junctions continuous between cells as they divide and elongate, and ultimately build a continuous functional tube.
    1. Cell Biology
    2. Medicine

    The Ca2+-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy

    Yang Guo, Ze-Yan Yu ... Boris Martinac
    The TRPM4 ion channel has been identified as an important component in the causation of mechanical pressure overload-induced pathological left ventricular hypertrophy, which is a powerful predictor of cardiovascular mortality.
    1. Cell Biology
    2. Medicine

    Pigmentation: Watching hair turn grey

    Michael P Philpott
    Analysing changes in hair pigmentation may lead to a better understanding of the impacts of ‘life events’ on human biology and aging.
    Version of Record
    Insight
    1. Cancer Biology
    2. Cell Biology

    Science Forum: Nanoscape, a data-driven 3D real-time interactive virtual cell environment

    Shereen R Kadir, Andrew Lilja ... John McGhee
    Computer visualization techniques developed for video games can be repurposed to enable viewers to explore cells and their environment in three dimensions.
    1. Cell Biology
    2. Developmental Biology

    Protein-based condensation mechanisms drive the assembly of RNA-rich P granules

    Helen Schmidt, Andrea Putnam ... Geraldine Seydoux
    P granule assembly depends in part on protein-protein interactions that drive condensation independent of RNA.
    1. Cell Biology

    Scaling of subcellular actin structures with cell length through decelerated growth

    Shane G McInally, Jane Kondev, Bruce L Goode
    The size of a subcellular structure, yeast actin cables, scales with the linear dimensions of the cell, which is achieved by feedback control of their growth rate.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics

    Amy R Strom, Ronald J Biggs ... Andrew D Stephens
    Micromanipulation experiments demonstrate that HP1α strengthens interphase and mitotic chromosome mechanics and maintains nuclear shape by chromatin crosslinking, separate from histone methylation.
    1. Cell Biology
    2. Immunology and Inflammation

    T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1

    Yujiao He, Zhiguo Yang ... Yingqiu Li
    T-cell receptor signaling actively regulates gating of the nuclear pore complex (NPC) in T cells by inducing translocation of protein kinase C-θ to the NPC to promote the sumoylation of RanGAP1.
    1. Cell Biology
    2. Computational and Systems Biology

    Microtubule reorganization during female meiosis in C. elegans

    Ina Lantzsch, Che-Hang Yu ... Stefanie Redemann
    Structural rearrangements of meiotic spindles during the transition from metaphase to anaphase can be controlled by local changes of microtubule dynamics, such as nucleation and/or turnover, and that katanin promotes microtubule turnover by severing microtubules near the chromosomes.