Browse our latest Cell Biology articles

Page 132 of 327
    1. Cell Biology

    CDK1 controls CHMP7-dependent nuclear envelope reformation

    Alberto T Gatta, Yolanda Olmos ... Jeremy G Carlton
    CHMP7 is phosphorylated by CDK1 upon mitotic entry, preventing interaction with LEM2 and inappropriate assembly during mitotic exit.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Genetically incorporated crosslinkers reveal NleE attenuates host autophagy dependent on PSMD10

    Jingxiang Li, Shupan Guo ... Haiyan Ren
    Transient interactions between NleE and PMSD10 suppress PSMD10 interaction with ATG7 to attenuate host autophagosome formation.
    1. Cell Biology
    2. Neuroscience

    An autoinhibitory clamp of actin assembly constrains and directs synaptic endocytosis

    Steven J Del Signore, Charlotte F Kelley ... Avital Adah Rodal
    Autoinhibition allows synaptic endocytic actin regulators to pre-deploy to synaptic membranes at high concentrations and constrains actin assembly to productive events.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair

    Shintaro Ide, Yoshihiko Kobayashi ... Tomokazu Souma
    Ferroptotic stress enhances the accumulation of damage-associated inflammatory proximal tubular cell state, thereby promoting maladaptive renal repair and the AKI-to-CKD transition.
    1. Cell Biology

    Pak1 kinase controls cell shape through ribonucleoprotein granules

    Joseph O Magliozzi, James B Moseley
    A newly discovered substrate of Pak1 kinase reveals novel mechanisms that control cell shape through regulated assembly of ribonucleoprotein granules.
    1. Cell Biology
    2. Immunology and Inflammation

    RTN3 inhibits RIG-I-mediated antiviral responses by impairing TRIM25-mediated K63-linked polyubiquitination

    Ziwei Yang, Jun Wang ... Ersheng Kuang
    RTN3 is upregulated upon RNA viral infection, in turn suppresses antiviral responses by impairing TRIM25-mediated RIG-I K63-linked polyubiquitination and decreases neutrophil populations and inflammatory infiltration, representing a novel inflammatory resolution.
    1. Cell Biology
    2. Developmental Biology

    The GNU subunit of PNG kinase, the developmental regulator of mRNA translation, binds BIC-C to localize to RNP granules

    Emir E Avilés-Pagán, Masatoshi Hara, Terry L Orr-Weaver
    The Drosophila PNG kinase controls mRNA translation at the oocyte-to-embryo transition, and its GNU activating subunit is shown here to bind translational repressors and be a component of RNP granules.
    1. Cell Biology
    2. Neuroscience

    Miro1-dependent mitochondrial dynamics in parvalbumin interneurons

    Georgina Kontou, Pantelis Antonoudiou ... Josef T Kittler
    Cell imaging and electrophysiology in the mouse hippocampus reveal a crucial role for the spatiotemporal regulation of mitochondrial dynamics in PV+ interneurons on cell morphology, network activity, and behavior.
    1. Cell Biology
    2. Neuroscience

    Sorting nexin-27 regulates AMPA receptor trafficking through the synaptic adhesion protein LRFN2

    Kirsty J McMillan, Paul J Banks ... Peter J Cullen
    An unbiased proteomic approach identifies a new regulator of AMPA receptor trafficking providing additional insight into synaptic transmission and plasticity.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Targeting an anchored phosphatase-deacetylase unit restores renal ciliary homeostasis

    Janani Gopalan, Mitchell H Omar ... John D Scott
    An anchored phosphatase-deacetylase complex participates in primary cilia development.