Browse our latest Cell Biology articles

Page 203 of 315
    1. Cell Biology

    Cell Division: Shining light on spindle positioning

    Andrea Serra-Marques, Sophie Dumont
    Optogenetic approaches are leading to a better understanding of the forces that determine the plane of cell division.
    Version of Record
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    1. Cell Biology
    2. Computational and Systems Biology

    Removing physiological motion from intravital and clinical functional imaging data

    Sean C Warren, Max Nobis ... Paul Timpson
    Image-based motion correction enables the use of fluorescence lifetime and other functional imaging modalities in an intravital and clinical context in the presence of physiological motion.
    1. Cell Biology
    2. Computational and Systems Biology

    Cell size sensing in animal cells coordinates anabolic growth rates and cell cycle progression to maintain cell size uniformity

    Miriam Bracha Ginzberg, Nancy Chang ... Marc W Kirschner
    Cells employ two strategies, adjusting both their cell cycle lengths and their growth rates in a size-dependent manner, to correct aberrations in cell size.
    1. Cell Biology
    2. Plant Biology

    Host autophagy machinery is diverted to the pathogen interface to mediate focal defense responses against the Irish potato famine pathogen

    Yasin F Dagdas, Pooja Pandey ... Tolga O Bozkurt
    Defense-related selective autophagy mediated by the antimicrobial autophagy cargo receptor NBR1/Joka2 is diverted to pathogen penetration sites to restrict plant colonization by the oomycete pathogen Phytophthora infestans.
    1. Cell Biology

    Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis

    Mark G Jones, Orestis G Andriotis ... Donna E Davies
    Nanoscale changes to individual collagen fibrils drive lung fibrosis.
    1. Cell Biology
    2. Developmental Biology

    Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia

    Kara L McKinley, Nico Stuurman ... Ronald D Vale
    The process of cytokinesis can allow cell lineages to intermix in mammalian epithelia, and cellular aspect ratio is a critical modulator of this behavior.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Temporal profiling of redox-dependent heterogeneity in single cells

    Meytal Radzinski, Rosi Fassler ... Dana Reichmann
    Analysis of aging yeast cells using the in-vivo roGFP2-based probe reveals redox-dependent heterogeneity, reflected in a bi-modal distribution of the oxidation status, differential growth and replication, as well as distinct proteomic and transcriptomic profiles.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    N-glycosylation in the protease domain of trypsin-like serine proteases mediates calnexin-assisted protein folding

    Hao Wang, Shuo Li ... Qingyu Wu
    N-glycans commonly present in the protease domains are required for calnexin-mediated protein folding and intracellular trafficking.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates

    Zhou Yu, Lauren E Surface ... Erin K O'Shea
    Identification of a transporter complex comprised of SLC37A3 and ATRAID is required for nitrogen-containing bisphosphonates to enter the cytosol from lysosomes and exert their therapeutic effects on bone.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Bone-Targeting Drugs: From vesicle to cytosol

    Michael J Rogers, Marcia A Munoz
    Drugs called bisphosphonates are used to treat a range of bone diseases, but how do they reach the enzymes that are their target?
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    Insight