A G protein in striatal neurons forms preassembled complexes with its downstream enzyme, adenylyl cyclase, which has implications for the pathophysiology of movement disorders.
António JM Santos, Ishier Raote ... Vivek Malhotra
Building on previous work (Nogueira et al., 2014), we describe a mechanism for the generation of a mega-carrier for the export of bulky procollagen from the endoplasmic reticulum.
A near-infrared light-stimulable optogenetic platform enables remote and wireless manipulation of calcium signaling and immune responses both in vitro and in vivo to achieve tailored function.
The availability of asparagine is important for cell growth and nascent peptide synthesis in certain sarcoma cells, and could be targeted therapeutically to inhibit tumor growth.
A eukaryotic cell model overcomes metabolic deficiencies within a complex, self-establishing community that enables the growth-relevant exchange of metabolic intermediates.
Control of neural stem cells by reactive oxygen species (ROS) provides a link between systemic shifts in oxygen tension and neuronal regeneration, and suggests an evolutionary driving force for the inherent ability of newts to regenerate their brain cells.
