Browse our latest Cell Biology articles

Page 80 of 325
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Adaptation to glucose starvation is associated with molecular reorganization of the circadian clock in Neurospora crassa

    Anita Szőke, Orsolya Sárkány ... Krisztina Káldi
    Molecular timekeeping in Neurospora crassa is robust even under severe limitation of carbon sources and the efficient adaptation to changing nutrient availability is dependent on the positive component of the circadian clock.
    1. Cell Biology
    2. Neuroscience

    Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones

    Chao Tan, Giovanni de Nola ... Pascal S Kaeser
    Hextuple knockout of key active zone proteins strongly reduces the pool of synaptic vesicles available for release, but synapse formation persists.
    1. Cell Biology

    A remarkable adaptive paradigm of heart performance and protection emerges in response to marked cardiac-specific overexpression of ADCY8

    Kirill V Tarasov, Khalid Chakir ... Edward G Lakatta
    Overexpression of hAC8 engages complex, coordinate adaptation 'circuity' that has evolved in mammalian cells to defend against stress that threatens health or life, and may be important for proper healing in disease states such as heart infarction or failure.
    1. Cell Biology
    2. Computational and Systems Biology

    Patterns of interdivision time correlations reveal hidden cell cycle factors

    Fern A Hughes, Alexis R Barr, Philipp Thomas
    Bayesian inference identifies hidden dynamics underlying noisy cell division data.
    1. Cell Biology

    Specific deletion of Axin1 leads to activation of β-catenin/BMP signaling resulting in fibular hemimelia phenotype in mice

    Rong Xie, Dan Yi ... Di Chen
    Specific gene knockout and signaling inhibition studies indicate the activation of β-catenin-bone morphogenetic protein signaling contributes to the development of fibular hemimelia disease.
    1. Cell Biology
    2. Physics of Living Systems

    Fixation can change the appearance of phase separation in living cells

    Shawn Irgen-Gioro, Shawn Yoshida ... Shasha Chong
    Different fixation protocols can both enhance and diminish the appearance of liquid–liquid phase separation (LLPS) droplets presenting a caveat in using fixed-cell imaging to diagnose LLPS.
    1. Cell Biology

    Metformin protects trabecular meshwork against oxidative injury via activating integrin/ROCK signals

    Lijuan Xu, Xinyao Zhang ... Yuanbo Liang
    Metformin, which promotes the recovery of damaged trabecular meshwork, is a potential intraocular pressure-lowering drug.
    1. Cell Biology
    2. Physics of Living Systems

    Dependence of diffusion in Escherichia coli cytoplasm on protein size, environmental conditions, and cell growth

    Nicola Bellotto, Jaime Agudo-Canalejo ... Victor Sourjik
    Diffusion of differently sized proteins in bacterial cytoplasm is nearly Brownian and consistent with the Stokes-Einstein relation, once protein shape and cell geometry are taken into account, and effects of various perturbation can be described as changes in cytoplasmic viscosity.
    1. Cell Biology

    Heterogeneous levels of delta-like 4 within a multinucleated niche cell maintains muscle stem cell diversity

    Susan Eliazer, Xuefeng Sun ... Andrew S Brack
    A gradient of Mib1-Dll4 within multinucleated muscle fibers maintains a continuum of metastable states within the muscle stem cell pool during tissue homeostasis.
    1. Cell Biology
    2. Developmental Biology

    Aurora A and cortical flows promote polarization and cytokinesis by inducing asymmetric ECT-2 accumulation

    Katrina M Longhini, Michael Glotzer
    Centrosomal Aurora A (AIR-1), together with cortical actomyosin flows, induces polarization of ECT-2, the activator of RHO-1, during polarization and cytokinesis, in order to promote furrow formation.