Browse our latest Computational and Systems Biology articles

Page 13 of 115
    1. Computational and Systems Biology
    2. Evolutionary Biology

    CoCoNuTs are a diverse subclass of Type IV restriction systems predicted to target RNA

    Ryan T Bell, Harutyun Sahakyan ... Eugene V Koonin
    Bacterial Type IV restriction-modification systems display remarkable, previously unnoticed diversity of complex gene and domain architectures, and are predicted to couple antiphage immunity with the abortive infection form of defense.
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    Deconstructing Complexity: A Computational Topology Approach to Trajectory Inference in the Human Thymus with tviblindi

    Jan Stuchly, David Novak ... Tomas Kalina
    Not revised
    Reviewed Preprint v1
    1. Computational and Systems Biology

    Improved clinical data imputation via classical and quantum determinantal point processes

    Skander Kazdaghli, Iordanis Kerenidis ... Philip Teare
    A new data imputation method that can be implemented quantumly allows for better and more reliable classifications.
    1. Neuroscience
    2. Computational and Systems Biology

    Testing the state-dependent model of subsecond time perception against experimental evidence

    Pirathitha Ravichandran-Schmidt, Joachim Hass
    Not revised
    Reviewed Preprint v1
    1. Computational and Systems Biology

    Heritable epigenetic changes are constrained by the dynamics of regulatory architectures

    Antony M Jose
    A foundation for analyzing epigenetic changes within the context of regulatory architectures that enable heredity.
    1. Neuroscience
    2. Computational and Systems Biology

    Anti-diuretic hormone ITP signals via a guanylate cyclase receptor to modulate systemic homeostasis in Drosophila

    Jayati Gera, Marishia Agard ... Meet Zandawala
    Not revised
    Reviewed Preprint v1
    1. Computational and Systems Biology
    2. Ecology

    Collaborative hunting in artificial agents with deep reinforcement learning

    Kazushi Tsutsui, Ryoya Tanaka ... Keisuke Fujii
    Collaborative hunting, characterized by the division of roles among predators, has emerged within a group of artificial agents through deep reinforcement learning.
    1. Computational and Systems Biology
    2. Developmental Biology

    The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults

    Arya Y Nakhe, Prasanna K Dadi ... David A Jacobson
    A mouse model of maturity-onset diabetes of the young illuminates that overactive TALK-1 channels limit β-cell calcium influx through membrane potential hyperpolarization, which blunts insulin secretion and causes glucose intolerance.
    1. Computational and Systems Biology

    Predicting metabolic modules in incomplete bacterial genomes with MetaPathPredict

    David Geller-McGrath, Kishori M Konwar ... Jason E McDermott
    MetaPathPredict is a novel bioinformatics tool that makes accurate predictions of KEGG module presence within highly incomplete bacterial genomes.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Experimental evolution for the recovery of growth loss due to genome reduction

    Kenya Hitomi, Yoichiro Ishii, Bei-Wen Ying
    Diversified genetic and transcriptional changes in parallel evolved Escherichia coli populations for improved growth revealed that the evolution complementing genome reduction was like all roads leading to Rome.
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