Browse our latest Computational and Systems Biology articles

Reaction-diffusion network modeling unveils general design principles that both stabilize cell polarization patterns and enable tunable interface localization, reconciling extensive experimental observations and deepening the understanding of asymmetric cell division.

A simple mathematical model, incorporating reversible deactivation of β-cells, can potentially explain the rapid onset and remission of a diabetes subtype, ketosis-prone diabetes.

Individuals with borderline personality disorder maintain rigid, distinct self-other representations, disrupting the bidirectional generalisation that underpins adaptive social learning and interpersonal trust.

A new framework for exploring the mechanisms underlying learning in cortical microcircuits is established.

Active vision dynamically refines spatiotemporal neural representations, optimising visual processing through scanning behaviour and non-associative learning, providing insights into efficient sensory encoding in dynamic environments.

The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.