Browse our latest Computational and Systems Biology articles

Page 13 of 119
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Benchmarking tRNA-Seq quantification approaches by realistic tRNA-Seq data simulation identifies two novel approaches with higher accuracy

    Tom Smith, Mie Monti ... Lajos Kalmár
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Computational and Systems Biology
    2. Neuroscience

    Robust, fast and accurate mapping of diffusional mean kurtosis

    Megan E Farquhar, Qianqian Yang, Viktor Vegh
    Mean kurtosis brain maps, derived from a sub-diffusion model with a novel clinically feasible two-diffusion-time acquisition, exhibit superior tissue contrast compared to the traditional diffusional kurtosis imaging (DKI).
    1. Neuroscience
    2. Computational and Systems Biology

    The Origin of Movement Biases During Reaching

    Tianhe Wang, Ryan J Morehead ... Richard B Ivry
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Computational and Systems Biology
    2. Developmental Biology

    Differential regulation of the proteome and phosphoproteome along the dorso-ventral axis of the early Drosophila embryo

    Juan Manuel Gomez, Hendrik Nolte ... Maria Leptin
    An encompassing resource of differentially phosphorylated proteins forms the basis for identifying missing links in cell fate determination and morphogenesis, including, for example, microtubules as mediators of different functions in cells along the dorso-ventral axis.
    1. Computational and Systems Biology

    TopOMetry systematically learns and evaluates the latent dimensions of single-cell atlases

    Davi Sidarta-Oliveira, Ana Domingos, Licio A Velloso
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Combining mutation and recombination statistics to infer clonal families in antibody repertoires

    Natanael Spisak, Gabriel Athènes ... Aleksandra M Walczak
    HILARy is a new algorithm for grouping B-cell receptor sequences into distinct lineages, a crucial task to analyze immune response and memory through repertoire sequencing.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Merging multi-omics with proteome integral solubility alteration unveils antibiotic mode of action

    Ritwik Maity, Xuepei Zhang ... Javier Sancho
    Like two peas in a pod but not exactly alike, similar molecules targeting the same bacterial protein behave differently, requiring systems biology and target deconvolution to gain better comprehension.
    1. Computational and Systems Biology

    Establishing comprehensive quaternary structural proteomes from genome sequence

    Edward Alexander Catoiu, Nathan Mih ... Bernhard Palsson
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Computational and Systems Biology
    2. Physics of Living Systems

    A mathematical model for ketosis-prone diabetes suggests the existence of multiple pancreatic β-cell inactivation mechanisms

    Sean A Ridout, Priyathama Vellanki, Ilya Nemenman
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Computational and Systems Biology

    Identifying images in the biology literature that are problematic for people with a color-vision deficiency

    Harlan P Stevens, Carly V Winegar ... Stephen R Piccolo
    Approximately 13% of figures in biology-related research articles are difficult for people with red/green colorblindness to decipher, but machine-learning models can help to identify these.
Newer articles Older articles