Browse our latest Computational and Systems Biology articles

Modern machine learning methods offer new techniques for analyzing complex vocal behavior like ultrasonic mouse calls and birdsong.

Mathematical modeling and data analysis show that, over evolutionary times, the yeast temporal program of replication strives to avoid stalling events and minimize interference between neighbor origins.

Computational modeling and a cell cycle-reporting axolotl reveal how spinal cord regeneration can be achieved by a signal that propagates 828 μm from the injury site during the first 85 hours post-amputation.

Convolutional neural networks are an effective tool for detecting archaic adaptive introgression from genomic data.

Prokaryotic TRADD-N and Death-like adaptor domains in diverse predicted apoptosis and immune systems from multicellular prokaryotes and metazoans indicate the common origin of key apoptosis mechanisms required for the stabilization of multicellularity.

Elucidating widespread and tissue-specific biological process alterations after myocardial infaction in metabolically active tissues using systems biology approaches.

A pushing force on the ankyrin repeat region of NompC leads to the gating of the mechanosensitive ion channel, which may enable cells to feel compression and shrinkage.

Heart attacks have a ripple effect on how other organs exchange biomolecules that help the heart respond to injury.

Arabidopsis shows extensive genetic diversity in germination time distributions, which can be explained by the underlying ABA/GA network functioning as a noisy bistable switch.

Cross-species transcriptomic analysis and high-throughput behavioral assays in a Drosophila model of Huntington's disease show that downregulation of glial genes involved in synaptic function compensates for disease-related excitotoxicity.