The circadian clock may help to control the development patterns which allow the florets on a sunflower head to go through their final stages of maturation at precisely the right time.
Shumin Wang, Eri O Maruyama ... Takamitsu Maruyama
The loss of miRNA-27a stimulates osteoclast-mediated bone resorption but does not affect osteoblast-mediated bone formation, leading to the development of osteoporosis in mice.
Divisive normalisation effects on decision making caused by distractor options can be reduced by stimulating the parietal cortex using transcranial magnetic stimulation.
During nephron regeneration, renal interstitial cells promote the proliferation of renal progenitor cells by secreting PGE2, thus forming the microenvironment of renal progenitor cells.
Merrick D Pierson Smela, Christian C Kramme ... George M Church
Making human stem cells express certain transcription factors can convert them into cells that are similar to ovarian granulosa cells, and perform several important functions of the ovary.
The ability of the adult zebrafish to replace damaged nephrons in the kidney depends on renal progenitor cells and renal interstitial cells working closely together.
In vitro model of germline specification in marmosets established by directed differentiation of induced pluripotent stem cells, which transcriptionally resemble pre-migratory primordial germ cells in vivo.
Valentyna Zinchenko, Johannes Hugger ... Anna Kreshuk
Unsupervised machine learning on the ultrastructure and shape of cells in volume electron microscopy yields a compact representation of cellular morphology that complements genetics-based cell type characterisation.
A new method allows researchers to automatically assign cells into different cell types and tissues, a step which is critical for understanding complex organisms.