A female specifically expressed new protein-coding gene that has emerged out of non-coding sequences without detectable signatures of adaptive evolution affects female pregnancy cycles.
Thomas A Sasani, Brent S Pedersen ... Aaron R Quinlan
Rates of germline mutation accumulation are highly variable across families of similar genetic ancestry, and post-zygotic mosaicism is a substantial source of de novo mutations.
Yamila N Torres Cleuren, Chee Kiang Ewe ... Joel H Rothman
Quantitative genetic analyses reveal remarkably broad genetic variation underlies the requirement for two critical regulatory inputs into a core embryonic gene regulatory network within one animal species.
Isabella Vlisidou, Alexia Hapeshi ... Nicholas R Waterfield
The insect pathogenic bacterium Photorhabdus has evolved astonishing nano-scale analogues of hypodermic syringes that it uses to inject toxins into host cells.
Interplay between histone demethylation and chromatin remodeling shapes the chromatin environment of the essential stress regulator ETHYLENE-INSENSITIVE2.
Sara Masachis, Nicolas J Tourasse ... Fabien Darfeuille
A genetic selection of toxicity suppressors coupled to high-throughput sequencing has captured metastable RNA structures that co-transcriptionally inhibit the translation of a bacterial toxin.
M Azim Ansari, Elihu Aranday-Cortes ... Vincent Pedergnana
Interferon lambda 4, a protein part of the innate immune response, drives major amino acids selection in patients chronically infected with hepatitis C virus.