Browse our latest Immunology and Inflammation articles

Simultaneous multimodal measurement of chromatin accessibility, gene expression, and protein expression provides a unified view of the molecular underpinnings of immune cell state in health and disease.

Early postmortem autopsy of COVID-19 patients shows high viral loads and damage of the lung, although extrapulmonary cells demonstrate no injury, they contribute to inflammation, hyper-coagulation, and multiple organ dysfunction.

Wnt signaling is revealed to be a regulator of macrophage inflammation-resolving state in atherosclerosis through a PGE2-mediated pathway.

Inducing neuronal mitochondrial activity during central nervous system inflammation counteracts inflammation-induced neuronal electron transport chain deficiency and calcium toxicity, thereby protecting against neuronal loss in a multiple sclerosis mouse model.

Malaria remodels the spleen to imprint tolerance and reduce pathology in subsequent infections.

COVID-19 survivors, who are at risk for vascular complications, would benefit from close monitoring and preventive therapy.

Structural and functional analysis of a new class of low-molecular-weight antibody fragments, derived from bovine immunoglobulins, reveals their therapeutic potential against C5, a target for refractory inflammatory diseases.

In vivo time lapse imaging reveals that microglial trogocytosis of presynaptic elements is regulated by the complement system which controls axon morphogenesis in the developing brain.

Stratification of COVID19 patients using quantitative metrics of seroconversion reveals distinct pathophysiological stages after SARS-CoV-2 infection, including key differences in immune cell types, inflammatory makers, and markers of organ function.

IL4i1 is an amino acid oxidase expressed in the mammalian immune system and snake venoms, which control diametrically opposite cell protection versus cell death pathways, respectively.