Browse our latest Microbiology and Infectious Disease articles

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    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    COVID-19 cluster size and transmission rates in schools from crowdsourced case reports

    Paul Tupper, Shraddha Pai ... Caroline Colijn
    Fitting a simple model of COVID-19 transmission to crowdsourced case report data allowed the estimation of mean cluster size and transmission rates in Canadian schools, as well as determining which interventions are most likely to limit transmission.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    The RAM signaling pathway links morphology, thermotolerance, and CO2 tolerance in the global fungal pathogen Cryptococcus neoformans

    Benjamin J Chadwick, Tuyetnhu Pham ... Xiaorong Lin
    In the fungal pathogen Cryptococcus neoformans, the RAM pathway, potentially through post-transcriptional regulation, plays an essential role in adaptation to host temperature and CO2.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Science Forum: A low-cost, open-source evolutionary bioreactor and its educational use

    Vishhvaan Gopalakrishnan, Dena Crozier ... Jacob G Scott
    The EVolutionary biorEactor (EVE) can be built for less than $200, and can be used to evaluate microbial population dynamics in the lab and to teach evolution in high schools.
    1. Ecology
    2. Microbiology and Infectious Disease

    Variation in the ACE2 receptor has limited utility for SARS-CoV-2 host prediction

    Nardus Mollentze, Deborah Keen ... Daniel G Streicker
    The success of angiotensin-converting enzyme 2 (ACE2)-based predictions of severe acute respiratory syndrome-associated virus 2 (SARS-CoV-2) host range stems from phylogenetic correlation, allowing development of scalable models which predict susceptibility to SARS-CoV-2 and other sarbecoviruses without requiring additional ACE2 sequencing.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    Acetylation of a fungal effector that translocates host PR1 facilitates virulence

    Jingtao Li, Xiaoying Ma ... Wenxing Liang
    Acetylation stabilizes a fungal effector to mis-localize a key defense protein, leading to compromised immunity of host plants.
    1. Microbiology and Infectious Disease

    An essential periplasmic protein coordinates lipid trafficking and is required for asymmetric polar growth in mycobacteria

    Kuldeepkumar R Gupta, Celena M Gwin ... E Hesper Rego
    Asymmetric growth in mycobacteria requires a protein that is involved in trafficking mycolic acids to the outer membrane.
    1. Microbiology and Infectious Disease

    T cell deficiency precipitates antibody evasion and emergence of neurovirulent polyomavirus

    Matthew D Lauver, Ge Jin ... Aron E Lukacher
    Loss of T cell control during persistent polyomavirus infection, in the setting of a limited antiviral antibody response, facilitates emergence of antibody-escape viruses carrying the potential for neurovirulence.
    1. Microbiology and Infectious Disease

    Phage resistance profiling identifies new genes required for biogenesis and modification of the corynebacterial cell envelope

    Amelia C McKitterick, Thomas G Bernhardt
    Using bacteriophages as probes, new genes involved in cell surface construction were identified in a class of bacteria that includes important pathogens like Mycobacterium tuberculosis.
    1. Microbiology and Infectious Disease
    2. Neuroscience

    A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice

    Reem Abdel-Haq, Johannes CM Schlachetzki ... Sarkis K Mazmanian
    Microbiome-diet interactions shape microglia reactivity in a mouse model of Parkinson's disease.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    High-throughput imaging and quantitative analysis uncovers the nature of plasmid positioning by ParABS

    Robin Köhler, Eugen Kaganovitch, Seán M Murray
    The ParABS system positions plasmids precisely within the cell but just below the threshold for oscillatory dynamics.