Browse our latest Microbiology and Infectious Disease articles

Page 89 of 168
    1. Microbiology and Infectious Disease

    Respiratory tissue-associated commensal bacteria offer therapeutic potential against pneumococcal colonization

    Soner Yildiz, João P Pereira Bonifacio Lopes ... Mirco Schmolke
    A respiratory tissue-associated commensal Lactobacillus strain confers colonization resistance to Streptococcus pneumoniae, when applied therapeutically in a post influenza virus super-infection model.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    A self-balancing circuit centered on MoOsm1 kinase governs adaptive responses to host-derived ROS in Magnaporthe oryzae

    Xinyu Liu, Qikun Zhou ... Zhengguang Zhang
    A phosphorylation circuitry balancing among kinase, transcription factor, transcription repressor, and phosphatase in response against host immunity during M. oryzae–rice interaction.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Functional reconstitution of a bacterial CO2 concentrating mechanism in Escherichia coli

    Avi I Flamholz, Eli Dugan ... David F Savage
    A bacterial CO2 concentrating mechanism enables Escherichia coli to fix CO2 from ambient air into biomass.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Autophagy compensates for Lkb1 loss to maintain adult mice homeostasis and survival

    Khoosheh Khayati, Vrushank Bhatt ... Jessie Yanxiang Guo
    Autophagy and Lkb1 work synergistically to maintain adult mouse homeostasis and survival.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy

    Joseph Shaw, Rajendra Gosain ... Stephen Griffin
    Exploiting virus-encoded ion channels as drug targets drove a multi-faceted approach to deriving potent small molecules targeting HCV p7, simultaneously providing new insights into its fundamental biology.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Genetic Engineering: Increasing the uptake of carbon dioxide

    Eric Franklin, Martin Jonikas
    A mechanism for concentrating carbon dioxide has for the first time been successfully transferred into a species that lacks such a process.
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    Insight
    1. Microbiology and Infectious Disease

    Glutamine metabolism modulates azole susceptibility in Trypanosoma cruzi amastigotes

    Peter C Dumoulin, Joshua Vollrath ... Barbara Burleigh
    Trypanosoma cruzi intracellular amastigotes exhibit rapid resistance to azoles, independent of genetic selection, which is dependent on metabolic state and mechanistically distinct from latency.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11

    Iga Kucharska, Elaine Thai ... Jean-Philippe Julien
    A comprehensive structural analysis of inhibitory murine antibody 3D11 binding to Plasmodium berghei circumsporozoite protein reveals common mechanisms of antibody evolution in mammals against Plasmodium parasites.
    1. Ecology
    2. Microbiology and Infectious Disease

    Metapopulation ecology links antibiotic resistance, consumption, and patient transfers in a network of hospital wards

    Julie Teresa Shapiro, Gilles Leboucher ... Jean-Philippe Rasigade
    Patterns of antibiotic use and the connectivity between wards are independently associated with the incidence of antimicrobial-resistant infections in hospital networks.
    1. Ecology
    2. Microbiology and Infectious Disease

    Antibiotics: Modelling how antimicrobial resistance spreads between wards

    Tjibbe Donker
    Moving patients between wards and prescribing high levels of antibiotics increases the spread of bacterial infections that are resistant to treatment in hospitals.
    Version of Record
    Insight