Browse our latest Microbiology and Infectious Disease articles

Page 90 of 169
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Asynchrony between virus diversity and antibody selection limits influenza virus evolution

    Dylan H Morris, Velislava N Petrova ... Colin A Russell
    Despite the virus' error prone polymerase, influenza virus antigenic evolution is rare, even in previously immune hosts, virus replication occurs before producing new antibodies.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Viruses: Neutralizing SARS-CoV-2

    Eric Poeschla
    Experiments with hybrid viruses are illuminating how SARS-CoV-2 can escape neutralizing antibodies.
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    Insight
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    A lung-on-chip model of early Mycobacterium tuberculosis infection reveals an essential role for alveolar epithelial cells in controlling bacterial growth

    Vivek V Thacker, Neeraj Dhar ... John D McKinney
    Time-lapse imaging and the modular recreation of host physiology reveal that alveolar epithelial cells, potential permissive infection sites for Mycobacterium tuberculosis, can restrict early bacterial growth via surfactant secretion.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Spreading of a mycobacterial cell-surface lipid into host epithelial membranes promotes infectivity

    CJ Cambier, Steven M Banik ... Carolyn R Bertozzi
    Applying bioorthogonal chemistry to the zebrafish/Mycobacterium marinum model of tuberculosis reveals that the virulence lipid PDIM must spread into epithelial cells in order for mycobacteria to establish infection.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Cross-talk between individual phenol-soluble modulins in Staphylococcus aureus biofilm enables rapid and efficient amyloid formation

    Masihuz Zaman, Maria Andreasen
    Inter-molecular cross-seeding between phenol-soluble modulins facilitates rapid and efficient self-assembly in Staphylococcus aureus biofilms revealing a complex molecular interplay between distinct phenol-soluble modulins orchestrating functional amyloid formation.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants

    Yiska Weisblum, Fabian Schmidt ... Paul D Bieniasz
    SARS-CoV-2 spike variants that resist neutralization by therapeutic antibodies or convalescent plasma can be generated in the laboratory and exist at low frequency in natural populations.
    1. Microbiology and Infectious Disease

    The malaria parasite sheddase SUB2 governs host red blood cell membrane sealing at invasion

    Christine R Collins, Fiona Hackett ... Michael J Blackman
    Genetic analysis identifies an enzyme of the malaria parasite that is required to seal its host red blood cell membrane upon invasion, a key requirement of this important intracellular pathogen.
    1. Microbiology and Infectious Disease

    Respiratory tissue-associated commensal bacteria offer therapeutic potential against pneumococcal colonization

    Soner Yildiz, João P Pereira Bonifacio Lopes ... Mirco Schmolke
    A respiratory tissue-associated commensal Lactobacillus strain confers colonization resistance to Streptococcus pneumoniae, when applied therapeutically in a post influenza virus super-infection model.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    A self-balancing circuit centered on MoOsm1 kinase governs adaptive responses to host-derived ROS in Magnaporthe oryzae

    Xinyu Liu, Qikun Zhou ... Zhengguang Zhang
    A phosphorylation circuitry balancing among kinase, transcription factor, transcription repressor, and phosphatase in response against host immunity during M. oryzae–rice interaction.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Functional reconstitution of a bacterial CO2 concentrating mechanism in Escherichia coli

    Avi I Flamholz, Eli Dugan ... David F Savage
    A bacterial CO2 concentrating mechanism enables Escherichia coli to fix CO2 from ambient air into biomass.