Physics of Living Systems

Physics of Living Systems

eLife reviews research in which approaches from the physical sciences are used to provide insights into the properties of biological systems and processes. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Physics of Living Systems

    Toward Stable Replication of Genomic Information in Pools of RNA Molecules

    Ludwig Burger, Ulrich Gerland
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience
    2. Physics of Living Systems

    Responses to membrane potential-modulating ionic solutions measured by magnetic resonance imaging of cultured cells and in vivo rat cortex

    Kyeongseon Min, Sungkwon Chung ... Jang-Yeon Park
    Magnetic resonance imaging, through its sensitivity to ionic environments that modulate membrane potential, enables noninvasive assessment of biological systems.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Heterogeneous efflux pump expression underpins phenotypic resistance to antimicrobial peptides

    Ka Kiu Lee, Urszula Łapińska ... Stefano Pagliara
    Sub-populations of non growing bacteria survive treatment with antimicrobial peptides by mounting an efflux response.
    1. Physics of Living Systems
    2. Evolutionary Biology

    Adaptations in wing morphology rather than wingbeat kinematics enable flight in small hoverfly species

    Camille Le Roy, Nina Tervelde ... Florian T Muijres
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Physics of Living Systems

    The cytoplasm of living cells can sustain transient and steady intracellular pressure gradients

    Majid Malboubi, Mohammad Hadi Esteki ... Guillaume Charras
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Physics of Living Systems

    Role of intercellular adhesion in modulating tissue fluidity

    Soumyadipta Ray, Santidan Biswas, Dipjyoti Das
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Designing biochemical circuits with tree search

    Pranav S Bhamidipati, Matthew Thomson
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience
    2. Physics of Living Systems

    The geometry and dimensionality of brain-wide activity

    Zezhen Wang, Weihao Mai ... Quan Wen
    Neural activity patterns in randomly sampled neuron groups statistically match whole-brain dynamics, revealing a scale-invariant organizational principle that enables robust and efficient computation across brain regions and species.
    1. Developmental Biology
    2. Physics of Living Systems

    Spectral decomposition unlocks ascidian morphogenesis

    Joel Dokmegang, Emmanuel Faure ... Madhav Mani
    The blueprint and narrative of shape formation during early development can be objectively observed by quantifying and analyzing whole-embryo dynamics.

Senior editors

  1. Felix Campelo
    The Institute of Photonic Sciences, Spain
  2. Aleksandra Walczak
    Ecole Normale Superieure, France
  3. See more editors