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Page 267 of 1,751
    1. Evolutionary Biology

    Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal development

    Tian Yue, Yongbo Guo ... Bing Su
    Comparative transcriptome analyses of human placenta reveal regulatory divergence between native highlanders and lowland immigrants living at high altitude, and a sex-biased pattern of genetic adaptation.
    1. Neuroscience

    Brain age has limited utility as a biomarker for capturing fluid cognition in older individuals

    Alina Tetereva, Narun Pat
    When used to capture fluid cognition, Brain Age likely fails to add substantially more information over and above chronological age and could miss up to around one-third of the variation.
    1. Developmental Biology
    2. Neuroscience

    A microRNA that controls the emergence of embryonic movement

    Jonathan AC Menzies, André Maia Chagas ... Claudio R Alonso
    A novel behavioural pipeline enables the quantitative analysis of the onset of movement in Drosophila embryos revealing that a microRNA modulates this process through regulatory effects in the sensory system.
    1. Neuroscience
    2. Computational and Systems Biology

    Episodic boundaries affect neural features of representational drift in humans

    Nimay Kulkarni, Bradley C. Lega
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Evolutionary trends of alternative splicing

    Rebeca de la Fuente, Wladimiro Díaz-Villanueva ... Andrés Moya
    Not revised
    Reviewed Preprint v1
    • Important
    • Inadequate
    1. Immunology and Inflammation

    The delayed kinetics of Myddosome formation explains why amyloid-beta aggregates trigger Toll-like receptor 4 less efficiently than lipopolysaccharide

    Bing Li, Prasanna Suresh ... David Klenerman
    Amyloid-beta aggregates and lipopolysaccharide differ in their kinetics of Myddosome formation and size of Myddosome formed, providing an explanation for the less efficient triggering of TLR4 observed with aggregates.
    1. Structural Biology and Molecular Biophysics

    Role of N343 glycosylation on the SARS-CoV-2 S RBD structure and co-receptor binding across variants of concern

    Callum M Ives, Linh Nguyen ... Elisa Fadda
    Viral evolution can lead to mutations that render specific glycosylation sites dispensable for folding and for supporting the protein's function, allowing changes in the shield, and in the immunogenic profile.
    1. Cell Biology
    2. Genetics and Genomics

    SCC3 is an axial element essential for homologous chromosome pairing and synapsis

    Yangzi Zhao, Lijun Ren ... Zhukuan Cheng
    SCC3 not only functions as a member of cohesin complex but also participates in homologous pairing and synapsis during rice meiosis.
    1. Medicine

    Phosphate as an adjunct to calcium in promoting coronary vascular calcification in chronic inflammatory states

    Gordon L Klein
    Phosphate and calcium from resorbing bone can find their way to the coronary circulation and contribute to atherosclerotic calcification of the blood vessels.
    1. Physics of Living Systems

    Quantifying gliding forces of filamentous cyanobacteria by self-buckling

    Maximilian Kurjahn, Antaran Deka ... Stefan Karpitschka
    The self-buckling behavior of filamentous cyanobacteria allowed a quantification of their propulsion forces, indicating that adhesion plays an important role in gliding motility.