Benson Otarigho, Anna Frances Butts, Alejandro Aballay
Molecular and genetics approaches reveal a dual regulatory role of neuronal G-protein-coupled receptor NPR-15 in both immunity and avoidance behavior, independent of aerotaxis, mediated by amphid sensory neurons, ASJ.
Application of a polyvinyl alcohol-based culture system reveals extensive differentiation but simultaneous robust murine hematopoietic stem cell (HSC) expansion, which are characterized by phenotypic, functional, and molecular properties shared with freshly isolated bone marrow HSCs.
Epilepsy caused by focal Pten deletion is only prevented when both mTOR complexes are simultaneously inhibited, but not alone, suggesting they play independent roles in the development of epilepsy.
Hugo Siegfried, Georges Farkouh ... Mélina L Heuzé
Depletion of VAPA in cancer cells induces defects in actin organization, adhesion dynamics and cell migration, together with a perturbation of phosphoinositide levels at the plasma membrane and a lack of anchoring of ER-PM contact sites to focal adhesions.
The dorsolateral prefrontal cortex represents different conflict types within an organized cognitive space of cognitive control, positioning more similar conflict types closer together.
A cellular experiment and animal model reveals that nifuroxazide can inhibit the expression of PD-L1 through the proteasome pathway, rather than at the genetic level.
Negative Gravitropic Response of roots (NGRs), pivotal for root gravitropic bending, are indispensable for the gravity-induced translocation of D6 protein kinase, a key regulator of PIN3 auxin efflux carrier activity.
Genetics, socioeconomic conditions, and family and school environments influence cognitive intelligence in children, and this impact may lead to the individual variability of the current and future PLEs.