Parahippocampal neurons increase their activity rates following navigational errors, and the error signal magnitude is related with overall task performance.
Ana C Chang-Gonzalez, Robert J Mallis ... Wonmuk Hwang
All-atom molecular dynamics simulations of an αβ T-cell receptor complexed with the major histocompatibility complex molecule presenting wild-type or mutant antigenic peptides reveal how it uses conserved framework motion to discriminate antigens by leveraging physiological force applied during immune surveillance.
The SP1/KLF transcription factor Huckebein controls endoreplication in the Drosophila salivary gland, ensuring proper morphogenesis during organ formation.
Robert J Bastidas, Mateusz Kędzior ... Raphael H Valdivia
Genetic and biochemical analyses show that Chlamydia protects secreted effectors necessary for its exit from infected cells, preventing them from undergoing ubiquitination and degradation.
Greg J Dodge, Alyssa J Anderson ... Barbara Imperiali
Structural, functional, and bioinformatics analyses further understanding of the initial steps of prokaryotic glycoconjugate biosynthesis catalyzed by the large class of membrane-embedded monotopic phosphoglycosyl transferase superfamily.
Metabolomic analyses have developed and validated serum androstenedione as a reliable and effective diagnostic and predictive biomarker for primary angle closure glaucoma in clinical routines.
Exploring tissue-specific regulation of gene expression with human-chimpanzee hybrid cells helps us understand how life evolves and what makes us human.
Artemis Koumoundourou, Märt Rannap ... Stefan Britsch
Molecular genetic, cell culture as well as electrophysiological analyses reveal a C1ql2/Neurexin3(25b+)-dependent molecular pathway through which Bcl11b controls critical functions of adult hippocampal mossy fiber synapses.
