Seemingly disparate working memory biases, including short-term serial and contraction biases, may arise from a common mechanism via the interaction of multiple networks, each operating over a distinct timescale.
The split mNeonGreen system enables fast and efficient endogenous tagging in human iPSCs and facilitates the study of proteins in human stem cells and differentiated cells by live imaging.
An unbiased approach unveils a non-canonical substrate of the known transporters, highlighting the mechanism behind the use of D-serine as a kidney biomarker.
A combination of patch clamp electrophysiology and FRET determine critical interactions between HCN4 channels and the ER resident protein LRMP and suggest a possible mechanism for reduced cAMP sensitivity.
Sensory hair cells in the inner ear use inhibitory G proteins with different regulators at different stages of development to break symmetry, adopt a proper orientation, and grow stereocilia.
Integrated analyses of acute myeloid leukemia genetics and epigenetics demonstrate that epigenetic evolution occurs in a convergent manner in the absence of DNA mutations at relapse post-chemotherapy.
Venkateshwari Varadharajan, Iyappan Ramachandiran ... J Mark Brown
MBOAT7 loss of function in hepatocytes contributes to ethanol-induced liver injury, offering crucial insights into the dysregulated lipid metabolism and impaired autophagy associated with advanced liver disease.
