Browse our latest research

Page 496 of 1,744
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Effects of an IgE receptor polymorphism acting on immunity, susceptibility to infection, and reproduction in a wild rodent

    Klara M Wanelik, Mike Begon ... Steve Paterson
    Genetic variation can have multiple effects on different phenotypic traits in organisms living in the natural environment.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Mir155 regulates osteogenesis and bone mass phenotype via targeting S1pr1 gene

    Zhichao Zheng, Lihong Wu ... Janak L Pathak
    Mir155 showed a catabolic effect on osteogenesis and bone mass phenotype via interaction with the S1pr1 gene, suggesting inhibition of Mir155 as a potential approach to bone regeneration and bone defect healing.
    1. Developmental Biology
    2. Neuroscience

    Molecular characterization of cell types in the squid Loligo vulgaris

    Jules Duruz, Marta Sprecher ... Simon G Sprecher
    Single-cell transcriptomics correlated with in situ gene expression analysis provide an overview of the diversity and molecular features of cell types in the squid Loligo vulgaris.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    A circular zone of attachment to the extracellular matrix provides directionality to the motility of Toxoplasma gondii in 3D

    Rachel V Stadler, Shane R Nelson ... Gary E Ward
    Parasites constrict as they propel themselves through the extracellular matrix one body length at a time, in a process highly reminiscent of host cell invasion.
    1. Neuroscience

    Population codes enable learning from few examples by shaping inductive bias

    Blake Bordelon, Cengiz Pehlevan
    Neural sensory representations impose an inductive bias over the space of learning tasks, allowing some tasks to be learned by a downstream neuron more sample-efficiently than others.
    1. Physics of Living Systems

    Predictive modeling reveals that higher-order cooperativity drives transcriptional repression in a synthetic developmental enhancer

    Yang Joon Kim, Kaitlin Rhee ... Hernan G Garcia
    The combination of theoretical modeling and quantitative live imaging revealed that the repressor proteins work cooperatively or anti-cooperatively depending on enhancer architecture.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub

    Martin Wilkinson, Oliver J Wilkinson ... Mark S Dillingham
    New cryoEM structures reveal how small bacteriophage proteins suppress bacterial immunity.
    1. Neuroscience

    Cortical activity during naturalistic music listening reflects short-range predictions based on long-term experience

    Pius Kern, Micha Heilbron ... Eelke Spaak
    When a person listens to music, their brain continually predicts upcoming notes, based on that person's likely lifelong musical experience.
    1. Developmental Biology
    2. Genetics and Genomics

    Urotensin II-related peptides, Urp1 and Urp2, control zebrafish spine morphology

    Elizabeth A Bearce, Zoe H Irons ... Daniel T Grimes
    Urp1 and Urp2 peptides, expressed in CSF-contacting neurons in the spinal canal, prevent abnormal curvature of the zebrafish spine.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Derivation and external validation of clinical prediction rules identifying children at risk of linear growth faltering

    Sharia M Ahmed, Ben J Brintz ... Daniel T Leung
    Clinical prediction rules could help identify children at risk of slowed growth after an episode of diarrheal illness, and these rules may be generalizable to all children, regardless of diarrhea status.