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Specific gene knockout and signaling inhibition studies indicate the activation of β-catenin-bone morphogenetic protein signaling contributes to the development of fibular hemimelia disease.

Advanced models of diffusion-weighted imaging data reveal that intra-axonal volume, especially in left temporoparietal and cerebellar white matter, relates to reading skills in a dataset of 983 children and adolescents.

New functionality in RELION-4.0 allows convenient structure determination from cryo electron tomography data to resolutions sufficient for de novo atomic modelling.

Different fixation protocols can both enhance and diminish the appearance of liquid–liquid phase separation (LLPS) droplets presenting a caveat in using fixed-cell imaging to diagnose LLPS.

Circulating immune cells reflect intra-tumoural immunity and can predict response to systemic therapy in head and neck cancer.

A common genomic deletion in various human cancers disrupts mitochondrial protein homeostasis in a way that might be targeted by existing drugs.

The ability to accurately predict a protein's structure gives us an entirely new way to annotate the human genome.

In the setting of CNS infection, meningeal lymphatic drainage promotes dendritic cell and T cell responses in the deep cervical lymph nodes but is not necessary for maintaining control of parasite in the brain.

Networked cardiac control, revealed through analysis of extended baseline-state multi-channel recordings, differentiates heart failure and normal regimes highlighting the promise of peripheral neurally based clinical interventions.

Metformin, which promotes the recovery of damaged trabecular meshwork, is a potential intraocular pressure-lowering drug.