HaDi MaBouDi, James AR Marshall ... Andrew B Barron
A fast and accurate decision-making strategy observed in bees, and reproduced in a neurally-grounded model, suggests a robust, risk-averse decision strategy suitable for when sampling and errors are both costly.
Consuelo Ibar, Krishna Chinthalapudi ... Kenneth D Irvine
Insight into the activity of β-heavy spectrin is provided by the discovery that it can compete with myosin for association with F-actin, which provides explanations for its influences on Hippo signaling and morphogenesis.
Guillem Torcal Garcia, Elisabeth Kowenz-Leutz ... Thomas Graf
A mutation in the lineage-determining regulator C/EBPα that increases the factor’s affinity for its partner PU.1 dramatically accelerates the velocity of B cell to macrophage transdifferentiation.
Ellen J Guss, Yulia Akbergenova ... J Troy Littleton
Loss of the extracellular matrix protein Perlecan leads to disruption of the neural lamella surrounding nerve bundles in Drosophila, resulting in axonal breakage and synaptic retraction of neuromuscular junctions.
Using unique data from five longitudinal UK birth cohorts, four distinct subsets of genetic variants were identified as differentially associated across wheezing phenotypes from infancy to adolescence with little evidence of genetic associations spanning across different phenotypes.
Kimberly E Roche, Johannes R Bjork ... Elizabeth A Archie
In baboon gut microbiota, most pairwise correlations in bacterial abundances are weak and negative, and bacterial correlation patterns are largely shared across hosts, rather than personalized to each hosts.
Optogenetics was used to reveal a novel role for the perirhinal cortex in regulating approach-avoidance behaviors under object-based motivational conflict.