Browse our latest research

Page 752 of 1,760
    1. Neuroscience

    Convergent and divergent brain structural and functional abnormalities associated with developmental dyslexia

    Xiaohui Yan, Ke Jiang ... Fan Cao
    Convergent structural and functional brain deficits associated with dyslexia were found in left superior temporal gyrus across languages, however, language-specific deficits were also identified.
    1. Cancer Biology

    Lipid droplets and ferritin heavy chain: a devilish liaison in human cancer cell radioresistance

    Luca Tirinato, Maria Grazia Marafioti ... Joao Seco
    Lipid Droplet accumulation is a fingerprint shared by different human cancer radioresistant cells and their biogenesis strongly depend on FTH1 presence.
    1. Evolutionary Biology
    2. Genetics and Genomics

    A modified fluctuation assay reveals a natural mutator phenotype that drives mutation spectrum variation within Saccharomyces cerevisiae

    Pengyao Jiang, Anja R Ollodart ... Kelley Harris
    Certain mutational signatures vary in their contribution to genetic variation across the yeast phylogeny due to genetically encoded natural mutator phenotypes whose activity can be directly measured in the lab.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective

    Mona Seifert, Subhas C Bera ... David Dulin
    High-throughput and ultra-stable magnetic tweezers reveal that Remdesivir induces a long-lived backtrack pause upon incorporation by the coronavirus polymerase, and SARS-CoV-2 is able to evade interferon-induced antiviral ddhCTP.
    1. Neuroscience

    Circadian regulation of vertebrate cone photoreceptor function

    Jingjing Zang, Matthias Gesemann ... Stephan CF Neuhauss
    Circadian expression of cone visual transduction genes and corresponding proteins correlates with circadian changes in photoresponse kinetics and visual behavior, linking circadian gene expression with physiological and behavioral rhythmicity.
    1. Epidemiology and Global Health

    Telomere length is associated with growth in children in rural Bangladesh

    Audrie Lin, Andrew N Mertens ... John M Colford Jr
    In a rural, low-income setting in Bangladesh, early-life telomere length was associated with concurrent growth.
    1. Cell Biology
    2. Neuroscience

    Activity-dependent Golgi satellite formation in dendrites reshapes the neuronal surface glycoproteome

    Anitha P Govind, Okunola Jeyifous ... William N Green
    Neuronal activity triggers the dispersal of the Golgi into dendritic Golgi satellites, leading to reshaping of the neuronal surface glycoproteome through processing of glycans to mature, sialic acid-containing forms.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Multiple introductions of multidrug-resistant typhoid associated with acute infection and asymptomatic carriage, Kenya

    Samuel Kariuki, Zoe A Dyson ... Gordon Dougan
    Carriage of MDR S. Typhi H58 sublineages that also cause acute disease provides understanding of the transmission dynamics of typhoid fever and maintenance of local pathogen populations in Kenya children.
    1. Neuroscience

    Calcium dependence of neurotransmitter release at a high fidelity synapse

    Abdelmoneim Eshra, Hartmut Schmidt ... Stefan Hallermann
    The Ca2+-dependence of vesicle priming, fusion, and replenishment at cerebellar mossy fiber boutons show a prominent Ca2+-dependent priming step, a shallow non-saturating dose-response curve up to 50 µM, and little Ca2+-dependence of sustained vesicle replenishment.
    1. Neuroscience

    Bayesian inference of population prevalence

    Robin AA Ince, Angus T Paton ... Philippe G Schyns
    Bayesian estimation of the proportion of the population that would show an effect in an experiment provides a broadly applicable alternative to standard null hypothesis tests on the population mean with several advantages.