Browse our latest research

Page 98 of 1,896
    1. Developmental Biology

    The NTR/prodrug revolution: Tools for controlling cell loss and regeneration

    Gha-Hyun J Kim, Michael Parsons
    Improved nitroreductase variants, optimized prodrugs, and careful experimental design enable scalable, precise cell ablation across model systems for disease modeling, regeneration studies, and high-throughput discovery.
    1. Neuroscience

    Growth in early infancy drives optimal brain functional connectivity which predicts cognitive flexibility in later childhood

    Chiara Bulgarelli, Anna Blasi ... The BRIGHT Study Team
    In Gambian infants, positive growth from 0 to 5 months of age predicted more mature brain networks, which in turn predicted cognitive outcomes at 3-5 years.
    1. Medicine
    2. Structural Biology and Molecular Biophysics

    Direct MRI of collagen

    Jason Daniel Van Schoor, Markus Weiger ... Klaas P Pruessmann
    The direct observation of collagen using magnetic resonance imaging is possible, presenting a new method to study the protein in vivo.
    1. Microbiology and Infectious Disease

    Quantitative RNA pseudouridine landscape reveals dynamic modification patterns and evolutionary conservation across bacterial species

    Letong Xu, Shenghai Shen ... Xin Deng
    Transcriptome-wide profiling of bacterial RNA pseudouridylation maps modification landscapes and nominates candidate regulatory sites, offering a resource and foundation for future mechanistic studies of Ψ function in bacteria.
    1. Genetics and Genomics
    2. Evolutionary Biology

    Somatic Programmed DNA Elimination is widespread in free-living Rhabditidae nematodes

    Caroline Launay, Eva Wenger ... Marie Delattre
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Immunology and Inflammation

    Cas9+ conditionally immortalized neutrophil progenitors as a tool for genome-wide CRISPR screening for neutrophil differentiation and function

    Robyn M Jong, Krystal L Ching ... Sarah A Stanley
    Cas9+ER-Hoxb8 neutrophils are a new tool for investigating neutrophil biology in vitro and in vivo.
    1. Developmental Biology

    HSD17B7 is required for the function of sensory hair cells by regulating cholesterol synthesis

    Yuqian Shen, Ziyang Wang ... Dong Liu
    HSD17B7-dependent cholesterol biosynthesis is essential for hair cell function, implicating HSD17B7 disruption in the pathogenesis of hearing loss.
    1. Cell Biology
    2. Neuroscience

    CO2-dependent opening of connexin 43 hemichannels

    Valentin Mihai Dospinescu, Alexander Mascarenhas ... Nicholas Dale
    Connexin43 is the most ubiquitously expressed connexin in the human body, and the CO2-dependent opening of Connexin43 hemichannels implies that CO2 may influence many physiological processes.
    1. Neuroscience

    Divergent spatiotemporal integration of whole-field visual motion in medaka and zebrafish larvae

    Yasuko Isoe, Yasmine Fatima Mabene ... Florian Engert
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Intron Retention Controls Localization of lncRNAs PURPL and MALAT1 to Promote Cell Proliferation and Migration

    Ioannis Grammatikakis, Chosita Norkaew ... Ashish Lal
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    • Compelling